Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Kyu-Sung KimDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Rami LeeGinsentology Research Laboratory, Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-0179-7563
Inyeong ParkNeuroimmunology Laboratory, Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea.
Sung-Hee HwangDepartment of Pharmaceutical Engineering, College of Health Sciences, Sangji University, Wonju 26339, Republic of Korea.
Yeshin KimDepartment of Neurology, Kangwon National University Hospital, Chuncheon 24289, Republic of Korea.ORCID 0000-0002-4643-5478
Jae-Won JangDepartment of Neurology, Kangwon National University Hospital, Chuncheon 24289, Republic of Korea.ORCID 0000-0003-3540-530X
Hyung-Seok KimDepartment of Neurosurgery, Chonnam National University Medical School, Research Institute of Medical Sciences, Gwangju 61469, Republic of Korea.ORCID 0000-0002-8297-9747
Seong-Min ChoiDepartment of Neurology, Chonnam National University Medical School, Jebong-ro, Gwangju 61469, Republic of Korea.
Sang Jin KimDepartment of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan 47392, Republic of Korea.
Hwa Jin ChoBusan & Gyeongnam Reference Laboratory, Department of Pathology, Seegene Medical Foundation, Busan 48792, Republic of Korea.ORCID 0000-0002-7613-1942
Ik-Hyun ChoDepartment of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0002-1036-0494
Jong-Hoon KimCollege of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-City 54596, Republic of Korea.
Do-Geun KimNeuroimmunology Laboratory, Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea.
Seung-Yeol NahGinsentology Research Laboratory, Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-9697-4763
Funding
National Research Foundation of Korea 2023R1A2C1003481
6 · The paper itself
Abstract
Ginseng, a traditional herbal medicine with a long history of use, is known to support human health, particularly by influencing brain function. Recent studies have identified gintonin, a lysophosphatidic acid (LPA) receptor ligand derived from ginseng, as a key bioactive. However, the specific LPA receptor subtypes targeted by gintonin in the human brain to exert its anti-Alzheimer's (AD) effects remain unclear. This study aimed to elucidate the LPA receptor subtype targeted by gintonin in the human cortex. Using a fluorescent gintonin conjugate, we investigated receptor binding in cortical samples from healthy individuals (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Gintonin Binds to Reduced LPA4 Receptor Subtype in Human Cortical Neurons in Alzheimer's Disease Brains. · full record | Socratic