Evidence map›Paper›PMID 40001528›Full record

ArticleBiomolecules2025

Melatonin-Mediated Circadian Rhythm Signaling Exhibits Bidirectional Regulatory Effects on the State of Hair Follicle Stem Cells.

Yu Zhang, Xuefei Zhao, Shuqi Li, Yanchun Xu, Suying Bai, Wei Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu ZhangCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.
Xuefei ZhaoCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0002-7368-0057
Shuqi LiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.
Yanchun XuCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.
Suying BaiCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0001-9686-3342
Wei ZhangCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.

Funding

Fundamental Research Funds for the Central Universities 2572017PZ02
6 · The paper itself

Abstract

The development and regulation of hair are widely influenced by biological rhythm signals. Melatonin plays a crucial role as a messenger in transmitting biological rhythm signals, and its impact on hair development has been well documented. During the process of hair follicle reconstruction, hair follicle stem cells (HFSCs) are the most important cell type, but the regulatory effect of melatonin on the state of HFSCs is still not fully understood. Therefore, it is necessary to conduct a more comprehensive characterization of the effects of melatonin on the state of hair follicle stem cells. The research results indicate that HFSCs express retinoic acid receptor-related orphan receptor alpha (

Indexed as

Circadian RhythmHair FollicleMelatoninSignal TransductionStem CellsAnimalsCells, CulturedForkhead Transcription FactorsGene Expression RegulationHumansMiceNuclear Receptor Subfamily 1, Group F, Member 1Forkhead Transcription FactorsMelatoninNuclear Receptor Subfamily 1, Group F, Member 1Foxc1hair follicle stem cellsmelatoninRORA

Identifiers

PMID40001528
PMCPMC11852975

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.