Evidence map›Paper›PMID 40001938›Full record

ArticleBiology2025

Early Outcomes of Right Ventricular Pressure and Volume Overload in an Ovine Model.

Hamida Al Hussein, Hussam Al Hussein, Marius Mihai Harpa, Simina Elena Rusu Ghiragosian, Simona Gurzu, Bogdan Cordos, Carmen Sircuta, Alexandra Iulia Puscas, David Emanuel Anitei, Cynthia Lefter and 3 more

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hamida Al HusseinDoctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0003-2509-3779
Hussam Al HusseinDepartment of Anatomy and Embryology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0002-4742-3583
Marius Mihai HarpaRegenerative Medicine Laboratory, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0002-9044-8866
Simina Elena Rusu GhiragosianDepartment of Pediatrics III, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0001-5460-8087
Simona GurzuDepartment of Morphopathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0003-3968-5118
Bogdan CordosRegenerative Medicine Laboratory, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0002-0042-866X
Carmen SircutaDepartment of Anesthesiology and Critical Care, Emergency Institute for Cardiovascular Diseases and Transplantation, 50 Gheorghe Marinescu Street, 540136 Targu Mures, Romania.ORCID 0009-0002-0996-284X
Alexandra Iulia PuscasDepartment of Cardiovascular Surgery, Emergency Institute for Cardiovascular Diseases and Transplantation, 50 Gheorghe Marinescu Street, 540136 Targu Mures, Romania.ORCID 0009-0001-0447-4129
David Emanuel AniteiDepartment of Cardiovascular Surgery, Emergency Institute for Cardiovascular Diseases and Transplantation, 50 Gheorghe Marinescu Street, 540136 Targu Mures, Romania.ORCID 0009-0002-9956-2312
Cynthia LefterDepartment of Anatomy and Embryology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0009-0003-7088-3742
Horatiu SuciuDepartment of Cardiovascular Surgery, Emergency Institute for Cardiovascular Diseases and Transplantation, 50 Gheorghe Marinescu Street, 540136 Targu Mures, Romania.ORCID 0000-0003-2390-4291
Dan SimionescuRegenerative Medicine Laboratory, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0002-7117-9904
Klara BrinzaniucDepartment of Anatomy and Embryology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania.ORCID 0000-0002-4852-6787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right ventricular (RV) failure is a common complication in multiple congenital heart disease (CHD), significantly increasing morbidity and mortality. Despite its impact, no therapies specifically target the failing RV. The growing population of CHD patients underscores the need to understand the pathophysiology of RV failure through preclinical research. This study aimed to develop an ovine model of RV failure induced by pressure and volume overload. A total of 14 juvenile sheep randomly underwent pulmonary artery banding (

Indexed as

ovine modelpulmonary artery bandingpulmonary regurgitationright ventricular failure

Identifiers

PMID40001938
PMCPMC11851871

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.