Evidence map›Paper›PMID 40001974›Full record

ArticleBiology2025

Difference Analysis Among Six Kinds of Acceptor Splicing Sequences by the Dispersion Features of 6-mer Subsets in Human Genes.

Yangming Si, Hong Li, Xiaolong Li

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yangming SiInner Mongolia Autonomous Region Key Laboratory of Biophysics and Bioinformatics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.ORCID 0000-0002-5004-0559
Hong LiInner Mongolia Autonomous Region Key Laboratory of Biophysics and Bioinformatics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.ORCID 0000-0001-6819-3038
Xiaolong LiInner Mongolia Autonomous Region Key Laboratory of Biophysics and Bioinformatics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.

Funding

National Natural Science Foundation of China 31860304
6 · The paper itself

Abstract

Identifying the sequence composition of different splicing modes is a challenge in current research. This study explored the dispersion distributions of 6-mer subsets in human acceptor splicing regions. Without differentiating acceptor splicing modes, obvious differences were observed across the upstream, core, and downstream regions of splicing sites for 16 dispersion distributions. These findings indicate that the dispersion value of each subset can effectively characterize the compositional properties of splicing sequences. When acceptor splicing sequences were classified into common, constitutive, and alternative modes, the differences in dispersion distributions for most of the XY1 6-mer subsets were significant among the three splicing modes. Furthermore, the alternative splicing mode was classified into normal, exonic, and intronic sub-modes, the differences in dispersion distributions for most of the XY1 6-mer subsets were also significant among the three splicing sub-modes. Our results indicate that dispersion values of XY1 6-mer subsets not only revealed the sequence composition patterns of acceptor splicing regions but also effectively identified the differences in base correlation among various acceptor splicing modes. Our research provides new insights into revealing and predicting different splicing modes.

Indexed as

acceptor splicing sequenceclassification of splicing modesdifference analysisdispersion featurehuman geneXY1 6-mer subset

Identifiers

PMID40001974
PMCPMC11853274

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.