Evidence map›Paper›PMID 40003111›Full record

ReviewEntropy (Basel, Switzerland)2025

Entropy and Complexity Tools Across Scales in Neuroscience: A Review.

Rodrigo Cofré, Alain Destexhe

Abstract readReview
In one paragraph

Review in Entropy (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rodrigo CofréCentre National de la Recherche Scientifique (CNRS), Institute of Neuroscience (NeuroPSI), Paris-Saclay University, 91400 Saclay, France.ORCID 0000-0002-7498-7122
Alain DestexheCentre National de la Recherche Scientifique (CNRS), Institute of Neuroscience (NeuroPSI), Paris-Saclay University, 91400 Saclay, France.ORCID 0000-0001-7405-0455

Funding

ANR FLAG-ERA program BrainAct projectHuman Brain Project H2020-945539Virtual Brain Twin project 101137289
6 · The paper itself

Abstract

Understanding the brain's intricate dynamics across multiple scales-from cellular interactions to large-scale brain behavior-remains one of the most significant challenges in modern neuroscience. Two key concepts, entropy and complexity, have been increasingly employed by neuroscientists as powerful tools for characterizing the interplay between structure and function in the brain across scales. The flexibility of these two concepts enables researchers to explore quantitatively how the brain processes information, adapts to changing environments, and maintains a delicate balance between order and disorder. This review illustrates the main tools and ideas to study neural phenomena using these concepts. This review does not delve into the specific methods or analyses of each study. Instead, it aims to offer a broad overview of how these tools are applied within the neuroscientific community and how they are transforming our understanding of the brain. We focus on their applications across scales, discuss the strengths and limitations of different metrics, and examine their practical applications and theoretical significance.

Indexed as

complexityentropymaximum entropy principleneuroscienceperturbational complexity index

Identifiers

PMID40003111
PMCPMC11854896

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.