ArticleInsects2025
Properties of "Stable" Mosquito Cytochrome P450 Enzymes.
Article in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cytochrome P450 and esterase genes associated with permethrin resistance in Aedes aegypti (Linnaeus, 1762).Molecular biology reports · 2025Article
- The CYP303A1 is essential in embryonic development ofFrontiers in physiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of insecticides is widespread in the control of debilitating mosquito-borne diseases. P450 enzymes (CYPs) play essential roles in mosquito physiological function but also in the enzymatic detoxification of xenobiotics. Broadly speaking, CYPs can be classified as "stable", meaning those that have no or very few paralogs, and "labile", constituting gene families with many paralogous members. The evolutionary dichotomy between "stable" and "labile" P450 genes is fuzzy and there is not a clear phylogenetic demarcation between P450s involved in detoxification and P450s involved in essential metabolic processes. In this study, bioinformatic methods were used to explore differences in the sequences of "stable" and "labile" P450s that may facilitate their functional classification. Genomic and sequence data of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.