Evidence mapPaperPMID 40004579Full record

ReviewJournal of clinical medicine2025

Diabetes Mellitus in Kidney Transplant Recipients: New Horizons in Treatment.

Maya Sanchez-Baya, Mónica Bolufer, Federico Vázquez, Nuria Alonso, Elisabet Massó, Javier Paul, Veronica Coll-Brito, Omar Taco, Paula Anton-Pampols, Rosana Gelpi and 8 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maya Sanchez-BayaDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0003-1689-9383
Mónica BoluferDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Federico VázquezDepartment of Endocrinology and Nutrition, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0001-6493-2374
Nuria AlonsoDepartment of Endocrinology and Nutrition, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Elisabet MassóDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Javier PaulDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Veronica Coll-BritoDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Omar TacoDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0001-9081-5665
Paula Anton-PampolsDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0003-3521-6066
Rosana GelpiDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Iara DaSilvaDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Ángela CasasDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Rosely RodríguezDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Maria MolinaDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0003-0033-4214
Laura CañasDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Anna VilaDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Jordi AraDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.
Jordi BoverDepartment of Nephrology, Hospital Universitario Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0003-3577-2273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) in kidney transplant recipients (KTR) is a risk factor for mortality, increases the risk of infections and, in the long term, can lead to graft loss due to diabetic kidney disease. A preventive approach applied to those on the waiting list could decrease the incidence of post-transplant DM (PTDM) by detecting those patients at risk, thus allowing strategies to minimize the probability of developing a New Onset Diabetes After Transplant (NODAT). On the other hand, modifications of immunosuppressive therapy may improve glucose control in patients with KTR. In recent years, two new classes of antidiabetic drugs and non-steroidal mineralocorticoid receptor antagonists have demonstrated cardiovascular and renal benefits in randomized clinical trials where the transplant population has not been represented. Because of the potential benefit expected in this population, the clinical use of glucagon-like peptide-1 receptor agonists (GLP-1RA), sodium-glucose cotransporter 2 inhibitors (SGLT2i) and finerenone is increasing in the kidney transplant setting. This review focuses on comprehensive pharmacological interventions in KTR with glucose metabolism disorders. In-depth knowledge in this area will allow prevention and identification of potential adverse effects or drug interactions in the clinical course of KTR with DM.

Indexed as

cardiovascular diseasediabetes mellituspost-transplant diabetes mellitus

Identifiers

PMID40004579
PMCPMC11856796

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.