Evidence map›Paper›PMID 40004697›Full record

ArticleJournal of clinical medicine2025

Melanocortin-4 Receptor Antagonism Inhibits Colorectal and Anaplastic Thyroid Cancer In Vitro and In Vivo.

Arianna Bandini, Marta Banchi, Paola Orlandi, Francesca Vaglini, Greta Alì, Gabriella Fontanini, Alessandra Ottani, Daniela Giuliani, Eleonora Vandini, Giulio Francia and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Arianna BandiniDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.ORCID 0009-0002-8966-7604
Marta BanchiDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.ORCID 0000-0003-0672-2066
Paola OrlandiDipartimento di Medicina Clinica e Sperimentale, Università di Pisa, 56126 Pisa, Italy.
Francesca VagliniDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.
Greta AlìDipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica, Università di Pisa, 56126 Pisa, Italy.ORCID 0000-0001-9258-3466
Gabriella FontaniniDipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica, Università di Pisa, 56126 Pisa, Italy.
Alessandra OttaniDipartimento di Scienze Biomediche, Metaboliche e Neuroscienze, Sezione di Farmacologia e Medicina Molecolare, Università di Modena e Reggio Emilia, 41121 Modena, Italy.
Daniela GiulianiDipartimento di Scienze Biomediche, Metaboliche e Neuroscienze, Sezione di Farmacologia e Medicina Molecolare, Università di Modena e Reggio Emilia, 41121 Modena, Italy.
Eleonora VandiniDipartimento di Scienze Biomediche, Metaboliche e Neuroscienze, Sezione di Farmacologia e Medicina Molecolare, Università di Modena e Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0001-7581-4437
Giulio FranciaBorder Biomedical Research Center, University of Texas at El Paso (UTEP), El Paso, TX 79968, USA.ORCID 0000-0002-3752-3070
Marco CarliDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.
Marco ScarselliDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.
Guido BocciDipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7120-9141

Funding

The role of breast cancer organ specific metastasis on the therapeutic impact of anti-cancer drugsSC1GM136630 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI FRANCIA, GIULIO · 2020 to 2023
$1.5M
NIGMS NIH HHS SC1 GM136630NIH HHS 1SC1GM136630-24A1University of Pisa Dimostratore Tecnologico 2018
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anaplastic thyroid cancercolorectal adenocarcinomain vitro modelin vivo modelMC4RML00253764SN-38vinorelbine

Identifiers

PMID40004697
PMCPMC11856147

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.