Evidence map›Paper›PMID 40004962›Full record

ReviewNutrients2025

The Effects and Mechanisms of Phytochemicals on Pain Management and Analgesic.

Milan Patel, Sayed Wahezi, Philippe Mavrocordatos, Alaa Abd-Elsayed

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Bioactive Potential ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Marine drugs · 2026
    Article
  4. Seasonal Variation in WildMolecules (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Milan PatelDepartment of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.
Sayed WaheziDepartment of Pain Managment, Montefiore Medical Center, Bronx, NY 10461, USA.
Philippe MavrocordatosSwiss Pain Institue, 1003 Lausanne, Switzerland.
Alaa Abd-ElsayedDepartment of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phytochemicals can be an essential treatment for chronic pain. This narrative review will summarize and critically analyze the evidence surrounding these substances in pain management. We will introduce phytochemicals, discuss their associated mechanisms, and comment on their viability for potential treatment. There have been decades of research on phytochemical therapies for pain management, but the authors limited the scope of the investigation to the last 25 years. This literature review will serve as a foundation for the pain practitioner to understand where these treatments fit in the paradigm for chronic pain treatment. Assess the integration of phytochemicals within pain management fully.

Indexed as

AnalgesicsChronic PainPain ManagementPhytochemicalsAnimalsHumansPhytotherapyAnalgesicsPhytochemicalshyperalgesiainflammationmechanism(s)nociceptionpain managementphytochemical(s)pro-inflammatory cytokines

Identifiers

PMID40004962
PMCPMC11858770

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.