Evidence map›Paper›PMID 40005000›Full record

Trial reportNutrients2025

Effect of Supplementation with a Specific Probiotic (

Caterina Anania, Viviana Matys, Simona Marra, Daniela De Canditiis, Francesca Olivero, Carlo Carraro, Anna Giugliano, Anna Maria Zicari, Maria Grazia Piccioni

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caterina AnaniaDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-9607-8632
Viviana MatysDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0009-0000-0568-3822
Simona MarraDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Daniela De CanditiisInstitute for the Application of Calculus (IAC)-CNR, 00185 Rome, Italy.ORCID 0000-0002-3022-3411
Francesca OliveroIndependent Researcher, 00100 Rome, Italy.ORCID 0000-0002-9363-455X
Carlo CarraroDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Anna GiuglianoDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Anna Maria ZicariDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Maria Grazia PiccioniDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by the appearance of recurrent eczematous lesions and intense itching. The World Allergy Organization (WAO) suggested the administration of probiotics in pregnant women at high risk of allergies in their children.

objectivesOur study aims to evaluate the role of administering the

methodsIt is a monocentric, randomized, double-blind, placebo-controlled trial with probiotic/placebo administration since the 36th week of gestation to mothers with atopy or a family history of atopy; the effects were evaluated over the first 12 months of the children's lives.

resultsNo severe adverse effects due to probiotic intake were reported in our cohort. Although proportionally fewer children with AD were in the probiotic group, the statistical analysis showed no significant differences between the probiotic and placebo groups. However, infants who developed the most severe forms of AD in the probiotic group showed a better clinical course during follow-up compared to those in the placebo group.

conclusionsIn conclusion, administering the probiotic

Indexed as

Bifidobacterium bifidumDermatitis, AtopicDietary SupplementsProbioticsAdultBreast FeedingDouble-Blind MethodFemaleHumansInfantMalePilot ProjectsPregnancyallergyatopic dermatitisinfancymicrobiotapregnancyprobioticsSCORAD

Identifiers

PMID40005000
PMCPMC11858544

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.