Evidence map›Paper›PMID 40005196›Full record

ArticleMolecules (Basel, Switzerland)2025

Development of Subcritical Water Extraction for Areca Alkaloids and Its Influence on the Structure of Areca Nut Husk.

Hongliang Zhao, Jinghao Yang, Jun Zeng, Bosheng Zhou, Min Yang, Xiaohong Yang, Ranfeng Sun

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongliang ZhaoSchool of Life and Health Sciences, Hainan University, Haikou 570228, China.ORCID 0009-0001-9148-4041
Jinghao YangInstitute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571199, China.
Jun ZengInstitute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571199, China.
Bosheng ZhouSchool of Life and Health Sciences, Hainan University, Haikou 570228, China.
Min YangSchool of Pharmacy, Gannan Medical University, Ganzhou 341000, China.
Xiaohong YangSchool of Life and Health Sciences, Hainan University, Haikou 570228, China.
Ranfeng SunSchool of Life and Health Sciences, Hainan University, Haikou 570228, China.

Funding

Hainan Provincial Natural Science Foundation of China 321RC663
6 · The paper itself

Abstract

The optimal process parameters of subcritical water extraction (SWE) for areca alkaloids in areca nut (AN) husk were described: extraction temperature of 110.87 °C, liquid-to-solid ratio of 18.98:1 and extraction time of 50.01 min. It was found that the factors influencing the process in order of significance were extraction time > extraction temperature > liquid-to-solid ratio. Considering practical conditions, the parameters were adjusted to the extraction temperature of 110 °C, the liquid-to-solid ratio of 19:1 and the extraction time of 50 min. The measured extraction rate was 81.7%, which is close to the predicted value, indicating that the extraction process optimized by Response Surface Methodology (RSM) is feasible. Meanwhile, preliminary results from XRD and FT-IR indicated that SWE had a significant influence on the structure of the AN husk, possibly by damaging some of the crystalline regions of cellulose in the AN husk or reducing the concentration of various functional groups. Overall, this study provided valuable insights in the SWE for areca alkaloids and its influence on the structure of areca nut husk, and further exploration for industrialization is still under development in our laboratory.

Indexed as

AlkaloidsArecaNutsPlant ExtractsWaterSpectroscopy, Fourier Transform InfraredTemperatureX-Ray DiffractionAlkaloidsPlant ExtractsWateralkaloidareca nutfiberhusksubcritical water extraction

Identifiers

PMID40005196
PMCPMC11857866

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.