ArticleFrontiers in veterinary science2025
Short-term effects of argon cold atmospheric plasma on canine corneas
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A dual-index framework for cold atmospheric plasma dosing: A meta-analysis of parametric control from volumetric redox flux to redox homeostatic status.Redox biology · 2026Pooled it
- Feasibility and Safety of Argon Cold Plasma Use as an Adjunctive Treatment for Corneal Disease in Dogs, Cats and Small Mammals: A Prospective Clinical Study.Veterinary ophthalmology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To analyse the effects of argon cold atmospheric plasma (CAP) on canine corneas. Methods: Healthy canine eyes ( Results: Corneal epithelization was complete and epithelial thickness was similar in all eyes. The number of perilimbal epithelial cell nuclei varied between groups with c1 = 22 ± 6, t0 = 13 ± 5, t2 = 15 ± 5 and t5 = 10 ± 4 nuclei/randomized fields and was lowest in t5, which was significantly different from t2 but not from t0. Ki-67 positive cells in the stroma varied between groups with c1 = 0.2 ± 0.45, t0 = 8 ± 12, t2 = 18 ± 12 and t5 = 10 ± 7 positive cells/section. More Ki-67 positive cells were found in t2 compared to t5. This was not significantly different from t0. Caspase-3 and α-SMA expression were similar in all treatment groups. Conclusion: Canine corneas treated with CAP showed similar corneal wound healing compared to untreated corneas
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.