Evidence map›Paper›PMID 40008064›Full record

ArticleEcology and evolution2025

Evidence for Pathogen-Driven Selection Acting on

Thomas Goeury, Ndeye Faye, Pascale Gerbault, Viktor Černý, Eric Crubézy, Jacques Chiaroni, Hacene Brouk, Lydie Brunet, Maxime Galan, Natasja G de Groot and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecology and evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas GoeuryLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.ORCID https://orcid.org/0009-0006-2938-6033
Ndeye FayeLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.
Pascale GerbaultLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.
Viktor ČernýInstitute of Archaeology of the Academy of Sciences of the Czech Republic Archaeogenetics Laboratory Czech Academy of Sciences Prague Czech Republic.
Eric CrubézyInstitut Universitaire de France UMR5288 CNRS University of Toulouse III Paul Sabatier Toulouse France.
Jacques ChiaroniADES UMR 7268 Aix Marseille University, EFS, CNRS Marseille France.
Hacene BroukService of Hemobiology and Blood Transfusion University Hospital Center Ibn Rochd of Annaba Faculty of Medicine Badji Mokhtar University of Annaba Annaba Algeria.
Lydie BrunetLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.
Maxime GalanCBGP UMR 1062 INRAE IRD CIRAD Montpellier SupAgro University of Montpellier Montpellier France.
Natasja G de GrootDepartment of Comparative Genetics and Refinement Biomedical Primate Research Centre (BPRC) Rijswijk the Netherlands.ORCID https://orcid.org/0000-0001-6699-9345
José Manuel NunesLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.
Alicia Sanchez-MazasLaboratory of Anthropology, Genetics and Peopling History (AGP), Department of Genetics and Evolution University of Geneva Geneva Switzerland.ORCID https://orcid.org/0000-0002-7714-2432

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African populations remain underrepresented in studies of human genetic diversity, despite a growing interest in understanding how they have adapted to the diverse environments they live in. In particular, understanding the genetic basis of immune adaptation to pathogens is of paramount importance in a continent such as Africa, where the burden of infectious diseases is a major public health challenge. In this study, we investigated the molecular variation of four Human Leukocyte Antigens (

Indexed as

AfricaHLAhuman molecular diversitymalariapathogen‐driven selectionplasmodium falciparum

Identifiers

PMID40008064
PMCPMC11850448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.