Biology of the avian respiratory system: development, evolutionary morphology, function and clinical considerations.

The respiratory biology of birds has been of interest to researchers for centuries, particularly owing to its dramatically heterogeneous structure, unusual ability for non-ventilatory structures to invade nearly all parts of the body (including the skeleton) in many taxa, and its exceptional efficiency under high-altitude hypoxia. Advances in imaging, experimental and developmental techniques, as well as recent palaeontological specimens have facilitated new discoveries, analyses and progress in the field. Comprehensively, this theme issue shows the origin of the modern avian respiratory system, current controversies and how the evolution of respiratory structures in birds has impacted their biology from the molecular, to the cellular, to the phylogenetic level. This collection of articles addresses progress the field has made, gaps in our knowledge and where the field needs to go, with a primary focus on adult and embryonic form and function but also touching on vocalization and clinical aspects of avian respiratory biology.This article is part of the theme issue 'The biology of the avian respiratory system'.