Evidence map›Paper›PMID 40010397›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2025

Adaptation and conservation of CL-10/11 in avian lungs: implications for their role in pulmonary innate immune protection.

Srinivasa Reddy Kunchala, Albert van Dijk, Edwin J A Veldhuizen, Henk P Haagsman, Sandra Orgeig

Abstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biology of the avian respiratory system: development, evolutionary morphology, function and clinical considerations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  2. Adaptation and conservation of CL-10/11 in avian lungs: implications for their role in pulmonary innate immune protection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srinivasa Reddy KunchalaClinical and Health Sciences, University of South Australia, Adelaide SA 5000, Australia.
Albert van DijkDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Edwin J A VeldhuizenDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Henk P HaagsmanDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Sandra OrgeigClinical and Health Sciences, University of South Australia, Adelaide SA 5000, Australia.ORCID 0000-0003-0849-2209

Funding

University of South Australia
6 · The paper itself

Abstract

The common avian origin of many zoonotic infections and epidemics warrants investigation into the mechanism of respiratory surface protection in reservoir species such as birds. Our recent molecular investigations on the evolution and pulmonary expression of an ancient family of proteins, the C-type lectins, have revealed unique molecular adaptations in the surfactant proteins avian SP-A1 (aSP-A1), aSP-A2 and aSP-C coupled with the loss of surfactant protein-D (SP-D) in the avian lineage. As surfactant proteins are members of the collectin family, a subgroup of the C-type lectins, an

Indexed as

Avian ProteinsCollectinsFinchesImmunity, InnateLungTurkeysAnimalsEvolution, MolecularPhylogenyAvian ProteinsCollectinsavian CL-10avian CL-11avian collectin protein evolutionavian non-surfactant proteinspulmonary innate immunityzoonotic respiratory infections

Identifiers

PMID40010397
PMCPMC12077231

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.