Evidence map›Paper›PMID 40011310›Full record

ReviewAAPS PharmSciTech2025

Electrospinning: A New Frontier in Peptide Therapeutics.

Jeyanthi L, Sivadharshini Kamaraj, Ruckmani Kandasamy, Shanmugarathinam Alagarsamy

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeyanthi LCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, Anna University, BIT Campus, Tiruchirappalli, 620024, Tamil Nadu, India.
Sivadharshini KamarajCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, Anna University, BIT Campus, Tiruchirappalli, 620024, Tamil Nadu, India.
Ruckmani KandasamyCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, Anna University, BIT Campus, Tiruchirappalli, 620024, Tamil Nadu, India.
Shanmugarathinam AlagarsamyCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, Anna University, BIT Campus, Tiruchirappalli, 620024, Tamil Nadu, India. shanmugarathinam@gmail.com.ORCID http://orcid.org/0009-0002-7983-5600

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nanofiber technology has recently undergone an unprecedented transformation, finding widespread utilities across diverse scientific disciplines. It is noteworthy that electrospinning approaches have emerged as an adaptable and successful approach to generate fibers ranging in rapidly as a class of therapeutic agents with a high level of target specificity. Peptides encounter several challenges as drugs, including swift breakdown by the body, rapid elimination from the bloodstream, inadequate stability, and restricted ability to cross cell membranes. This renders it challenging to employ them as drugs. However, electrospun nanofibers might address these problems. This review explores the promising potential of electrospinning nanofibers for peptide delivery. We delve into recent advancements in this technique, highlighting its effectiveness in overcoming challenges associated with peptide drug delivery. It provides an analysis of the trends identified in the use of the electrospinning technique and its role in peptide drug delivery systems, based on a review of data collected over a period of five to seven years.

Indexed as

Drug Delivery SystemsNanofibersPeptidesAnimalsDrug CarriersHumansTechnology, PharmaceuticalDrug CarriersPeptideselectrospinningelectrospun nanofibernanofiberpeptide deliverypeptide nanofiber

Identifiers

PMID40011310

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.