Evidence map›Paper›PMID 40011380›Full record

ArticleTherapeutic innovation & regulatory science2025

Designing a Patient Preference Study on Subcutaneous Medical Devices: Incorporating Health Authority Scientific Advice and Patient Perspectives.

Marie Picci, Nigel S Cook, Byron Jones, Mo Zhou, Conny Berlin, Christine Sturchler, Clemence Martinez, Irene Garcia Baena, Lauren Ziegler, Harriet Gaunt and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic innovation & regulatory science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marie PicciNovartis Pharma AG, Basel, Switzerland.
Nigel S CookNovartis Pharma AG, Basel, Switzerland.
Byron JonesNovartis Pharma AG, Basel, Switzerland. byron.jones_ext@novartis.com.
Mo ZhouNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Conny BerlinNovartis Pharma AG, Basel, Switzerland.
Christine SturchlerNovartis Pharma AG, Basel, Switzerland.
Clemence MartinezNovartis Pharma AG, Basel, Switzerland.
Irene Garcia BaenaNovartis Pharma AG, Basel, Switzerland.
Lauren ZieglerNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Harriet GauntAdelphi Research, Bollington, Cheshire, UK.
Brad MasonAdelphi Values Patient-Centered Outcomes, Bollington, Cheshire, UK.
Dominique HamerlijnckAtini, Amsterdam, Netherlands.
Yoshiyuki MajimaPanCAN, Chiyodaku, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes the planning of a patient preference study for evaluating device features for the subcutaneous (SC) delivery of high dose/large volume (e.g., > 2 ml) of drugs. Multiple sources, including qualitative patient interviews, the involvement of patient partners, and solicitation of advice from the US Food and Drugs Administration (FDA), were used to refine the attributes and levels in the development of a preference study protocol to investigate what Multiple Sclerosis (MS) patients consider important regarding medical device features for high dose SC administration.

Indexed as

Multiple SclerosisPatient PreferenceHumansInjections, SubcutaneousResearch DesignUnited StatesUnited States Food and Drug AdministrationDevice featuresPatient experience dataPatient preferencesScientific adviceSubcutaneous delivery

Identifiers

PMID40011380
PMCPMC12018491

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.