Evidence map›Paper›PMID 40011496›Full record

ArticleScientific reports2025

Association between serum vitamin A and bone mineral density in adolescents.

Li Ling

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Li LingDepartment of Pediatrics, Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, China. wugui_dt@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin A is essential for growth and development, immune function, vision, and gene expression. The association between adult bone mineral density (BMD) and vitamin A has been extensively studied, the findings are heterogeneous. Studies investigating the direct correlation between vitamin A and BMD in children are, nonetheless, few. The purpose of this study is to investigate the link between vitamin A and BMD in American teenagers. In this cross-sectional investigation, 6,002 adolescents between the ages of 12 and 19 participated in the National Health and Nutrition Examination Survey (NHANES), which was performed between 2001 and 2006. The relationship between serum Vitamin A and BMD was assessed using a weighted multivariate linear regression model and smooth-fitting curves. Increased serum Vitamin A is substantially positively linked with BMD of the thoracic spine, lumbar spine, pelvis, trunk bone, and total BMD after controlling for pertinent factors. According to the threshold effect curve, the impact of Vitamin A is significant (P < 0.05) when it is below the saturation threshold. Males exhibit a stronger positive association, according to subgroup analysis. According to our research, there is a strong positive connection and saturation effect between serum Vitamin A and BMD in American adolescents.

Indexed as

Bone DensityVitamin AAdolescentChildCross-Sectional StudiesFemaleHumansMaleNutrition SurveysYoung AdultVitamin AAdolescentsBone mineral densityNHANESSerum vitamin A

Identifiers

PMID40011496
PMCPMC11865262

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.