ReviewMini reviews in medicinal chemistry2025
Innovative Horizons in Drug Design: Exploring the Synthesis and Medicinal Properties of Heterocyclic Schiff Bases. A Review.
Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer's agents withJournal of enzyme inhibition and medicinal chemistry · 2026Article
- Adjunctive therapeutic strategy for in-stent thrombosis:RSC advances · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schiff bases are an important scaffold for designing drug development. They are characterized by having a carbon-nitrogen double bond. This double bond is synthesized by different synthetic schemes by both the aromatic and aliphatic chains. Bases inspired chemists due to their versatile importance in drug discovery and drug development. A large number of drugs are designed through the heterocyclic Schiff base moieties. This review highlighted the importance of Schiff bases concerning their bioactive importance in drug design. Moreover, amide-iminol tautomerism is a significant tool for the high biological importance of Schiff bases due to the presence of the C=N bond. Furthermore, the reported synthesized heterocyclic scaffolds Schiff bases have a wide range of biological importance. Due to this different biological importance, such as antimicrobial, anticonvulsant, analgesic, antioxidant, antimalarial, anti-inflammatory, anticancer, antidiabetic, and antileishmanial properties, the researcher has shown their interest by synthesizing different heterocyclic Schiff bases. In this review article, biologically active heterocyclic Schiff bases were reviewed intensively concerning drug design and drug development.
Indexed as
Identifiers
40012381What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.