ArticleFrontiers in public health2025
Association between frailty and postherpetic neuralgia in the older adult with herpes zoster.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- [StagingZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Review
- CT-Guided Dorsal Root Ganglion Pulsed Radiofrequency Alone, with Ozone, or with Platelet-Rich Plasma for Postherpetic Neuralgia: A Randomized Controlled Trial.Journal of pain research · 2026Article
- The relationship between chronic pain and health-related quality of life: the mediating roles of frailty and depression in chronic disease patients.Frontiers in public health · 2025Article
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chronic pain is closely related to frailty. Methods: A total of 300 older adult patients diagnosed with HZ were selected and admitted to our hospital in 2024. A basic data questionnaire gathered baseline information, and the FRAIL scale was employed to evaluate their initial frailty status. Patients who were non-frail at baseline were followed up for 3 months. They were categorized into the PHN group and the non-PHN group based on the occurrence of neuropathic pain during follow-up. Diverse scales were employed to evaluate frailty, nutritional status, anxiety, and depression among participants. The Chi-square or Kruskal-Wallis tests were employed to compare the two groups. The logistic regression model was undertaken to explore the impact of PHN on frailty. Results: Among the 300 older adult patients with HZ who satisfied the inclusion criteria, follow-up data were collected from 215 patients, comprising 85 cases in the PHN group and 130 cases in the non-PHN group. A prospective analysis of the 215 baseline non-frail patients showed that the incidence of frailty in older HZ patients was 14.9%. Univariate analysis revealed that the distributions of lesion site, lesion area, depression status, anxiety status, COPD, and nutritional score were statistically significant between the two groups (χ Conclusion: Postherpetic neuralgia increases the risk of frailty and is a significant factor influencing the progression of frailty in the older adult.
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