Evidence map›Paper›PMID 40017586›Full record

ArticlePathogens & immunity2024

When Extracellular Vesicles Go Viral: A Bird's Eye View.

Leonid B Margolis, Yoel Sadovsky

Abstract read
In one paragraph

Article in Pathogens & immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leonid B MargolisFaculty of Natural Sciences and Medicine, Ilia State University, Tbilisi, Georgia.
Yoel SadovskyMagee-Womens Research Institute, Department of OBGYN and Reproductive Sciences, Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.

Funding

Exosome Based Placental Maternal CommunicationR37HD086916 · NICHD · STANFORD UNIVERSITY · PI Yoel Sadovsky · 2017 to 2026
$3.5M
Acoustofluidic Separation of Placental Nanovesicle Subpopulations in Obstetrical DiseasesR01HD103727 · NICHD · STANFORD UNIVERSITY · PI HUANG, TONY JUN, SADOVSKY, YOEL · 2021 to 2025
$2.6M
NICHD NIH HHS R01 HD103727NICHD NIH HHS R37 HD086916
6 · The paper itself

Abstract

The science of extracellular vesicles (EVs) is a rapidly growing field that spans multiple aspects of normal physiology and pathophysiology. EVs play a critical role in most basic biological processes of cell-cell communications under normal conditions and in disease. EVs have "gone viral" not only in terms of research popularity, but also in our realization that they exhibit an elaborate crosstalk with viruses, particularly with the enveloped ones, which are also extracellular vesicles that are released by cells as a part of their virulence cycle yet are replicative. Here, we highlight some of the complexities underlying EV-virus crosstalk and pathways and provide our insights on key challenges from the viewpoint of EV biology.

Indexed as

antagonismcell communicationcooperativityExtracellular vesiclesviruses

Identifiers

PMID40017586
PMCPMC11867185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.