Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
David J PeelerDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0003-2441-6409
Rujie SunDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0001-6136-7277
Ceren KütahyaDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0002-8680-6536
Patrick PeschkeDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0009-0006-4097-7256
Kun ZhouDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0003-4109-5926
Giulia BrachiDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0002-0785-2332
Jonathan YeowDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0003-3709-5149
Omar Rifaie-GrahamDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0003-1403-0537
Jonathan P WojciechowskiDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0002-6272-515X
Thomas F F Fernandez DebetsDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0009-0007-6951-6514
Vernon LaLoneDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0001-6043-8993
Xin SongDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0003-4017-9685
Krunal PolraDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.
Paul F McKayDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0001-5195-6254
John S TregoningDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0001-8093-8741
Robin J ShattockDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0002-4936-1718
Molly M StevensDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.ORCID https://orcid.org/0000-0002-7335-266X
Funding
Gates Foundation INV-003863HORIZON EUROPE Marie Sklodowska-Curie Actions 101027174HORIZON EUROPE Marie Sklodowska-Curie Actions 839137HORIZON EUROPE Marie Sklodowska-Curie Actions 890854HORIZON EUROPE Marie Sklodowska-Curie Actions 893158Medical Research Council MR/R015651/1Royal Academy of Engineering CiET2021∖94
6 · The paper itself
Abstract
Two-photon polymerization (2PP) 3D printing enables top-down biomaterial synthesis with nanoscale spatial resolution for de novo design of monodisperse injectable drug delivery systems. Spatiotemporal Controlled Release Inks of Biocompatible polyEsters (SCRIBE) is a novel poly(lactic-co-glycolic acid)-triacrylate resin family with sub-micron resolution and tuneable hydrolysis that addresses the limitations of current 2PP resins. SCRIBE enables the direct printing of hollow microparticles with tuneable chemistry and complex geometries inaccessible to molding techniques, which are used to engineer controlled protein release in vitro and in vivo. SCRIBE microparticles are used to modulate antibody titers and class switching as a function of antigen release rate and extend these findings to enable a single-injection vaccine formulation with extended antibody induction kinetics. Demonstrating how the chemistry and computer-aided design of 2PP-printed microparticles can be used to tune responses to biomacromolecule release in vivo opens significant opportunities for a new generation of drug delivery vehicles.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.