Evidence map›Paper›PMID 40019733›Full record

ArticleAnnals of nuclear medicine2025

A low-dose protocol in pediatric

Ha Wu, Guobing Liu, Xiemei Ruan, Biying Zhang, Zheng Zhe, Hongcheng Shi

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Article in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ha Wu *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 in Fenglin Road, Shanghai, 200032, China.
Guobing Liu *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 in Fenglin Road, Shanghai, 200032, China.
Xiemei RuanDepartment of Nuclear Medicine, Children's Hospital, Fudan University, Shanghai, 201102, China.
Biying ZhangDepartment of Nuclear Medicine, Children's Hospital, Fudan University, Shanghai, 201102, China.
Zheng ZheDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 in Fenglin Road, Shanghai, 200032, China.
Hongcheng ShiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, No. 180 in Fenglin Road, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.

Funding

Chinese National Key Clinical Specialty Program YWP2022-007Innovative Medical Device Application Demonstration Program of Shanghai Municipal Commission of Economy and Informatization 23SHS01200Key Program of Ministry of Industry and Information Technology of China CEIEC-2022-ZM02-0219National Key R&D Program of China 2022YFC2406902National Key R&D Program of China 2022YFC2406904
6 · The paper itself

Abstract

objectiveTo explore the feasibility of a low-dose

methodsA retrospective analysis was conducted on 112 pediatric patients who underwent a full-dose (3.7 MBq/kg)

resultsIn G2.0 and G3.0, all cases (112/112) achieved an image score of ≥ 3 and a lesion detection rate of 100% (98/98). There were no significant differences in SNR between G2.0 and G3.0 (11.09 ± 2.31 vs. 11.88 ± 2.58, p = 0.39), nor between age groups ≤ 5 years and 6-10 years groups (9.52 ± 3.16 vs. 9.53 ± 3.19, p = 0.99). In G3.0', 98.2% of cases (54/55) had an image score ≥ 3 and a lesion detection rate of 100% (43/43). The SNR of every age group for G3.0' was comparable to that of G2.0, and no significant differences between ≤ 5 years and 6-10 years groups (9.32 ± 1.94 vs. 9.99 ± 2.28, p = 0.82).

conclusionsA 2.5 MBq/kg dose with a 3.0 min/bed acquisition protocol is feasible for

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyRadiation DosageAdolescentChildChild, PreschoolFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedInfantMaleRetrospective StudiesSignal-To-Noise RatioFluorodeoxyglucose F18Image qualityLow-dosePediatricPET/CT imaging

Identifiers

PMID40019733

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.