Evidence map›Paper›PMID 40021279›Full record

ReviewCritical care clinics2025

Novel Strategies to Promote Intensive Care Unit Recovery via Personalized Exercise, Nutrition, and Anabolic Interventions.

Ashley L Artese, Hilary M Winthrop, Megan Beyer, Krista L Haines, Jeroen Molinger, Amy M Pastva, Paul E Wischmeyer

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Critical care clinics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashley L ArteseDepartment of Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, FL, USA.
Hilary M WinthropDuke Office of Clinical Research, Duke University School of Medicine, Durham, NC, USA.
Megan BeyerDepartment of Anesthesiology, Duke University School of Medicine, Durham, NC, USA.
Krista L HainesDepartment of Surgery, Division of Trauma, Critical Care, and Acute Care Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Jeroen MolingerHuman Pharmacology and Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Amy M PastvaDepartment of Orthopaedic Surgery, Division of Physical Therapy, Duke University School of Medicine, Durham, NC, USA; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, USA.
Paul E WischmeyerDepartment of Anesthesiology and Surgery, Duke University, Durham, NC, USA. Electronic address: Paul.Wischmeyer@Duke.edu.

Funding

Remotely Monitored, Mobile health-supported High Intensity Interval Training after COVID-19 Critical Illness (REMM HIIT-Covid19)R01HD107103 · NICHD · DUKE UNIVERSITY · PI Amy M Pastva, PAUL E WISCHMEYER · 2021 to 2026
$4.1M
NICHD NIH HHS R01 HD107103
6 · The paper itself

Abstract

Survivors of critical illness experience significant morbidity, reduced physiologic reserve, and long-term complications that negatively impact quality of life. Although rehabilitative treatments are beneficial during early recovery, there is limited evidence regarding effective multimodal rehabilitation, nutrition, and anabolic nutrient/agent strategies for improving long-term outcomes. This review discusses novel personalized rehabilitation, nutrition, and anabolic nutrient/agent (ie, creatine, β-hydroxy-β-methylbutyrate, testosterone) approaches that allow for precise exercise and nutrition prescription and have potential to improve patient care, address continued medical needs, and optimize long-term recovery. Continued research is needed to further evaluate effectiveness and implementation of these strategies throughout the continuum of care.

Indexed as

Anabolic AgentsCritical CareCritical IllnessExercise TherapyIntensive Care UnitsNutrition TherapyPrecision MedicineExerciseHumansAnabolic AgentsCardiopulmonary exercise testingCPET testingCreatineCritical illnessExerciseNutritionRehabilitationTestosterone

Identifiers

PMID40021279
PMCPMC12199169

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.