Evidence mapPaperPMID 40025338Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

TRPM6 in murine kidneys-of targets and antibodies.

Colya N Englisch, Coline M Diebolt, Emilie Kirstein, Vanessa Wahl, Philipp Wartenberg, Dirk Schaudien, Anja Beckmann, Matthias W Laschke, Gabriela Krasteva-Christ, Thomas Gudermann and 3 more

Abstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Colya N EnglischInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany.
Coline M DieboltInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany.
Emilie KirsteinInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany.
Vanessa WahlInstitute of Pharmacology, Saarland University, 66421, Homburg/Saar, Germany.
Philipp WartenbergInstitute of Pharmacology, Saarland University, 66421, Homburg/Saar, Germany.
Dirk SchaudienFraunhofer Institute for Toxicology and Experimental Medicine, 30625, Hannover, Germany.
Anja BeckmannInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany.
Matthias W LaschkeInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Gabriela Krasteva-ChristInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany.
Thomas GudermannWalther-Straub Institute of Pharmacology and Toxicology, Ludwig Maximilian University Munich, Munich, Germany.
Vladimir ChubanovWalther-Straub Institute of Pharmacology and Toxicology, Ludwig Maximilian University Munich, Munich, Germany.
Ulrich BoehmInstitute of Pharmacology, Saarland University, 66421, Homburg/Saar, Germany.
Thomas TschernigInstitute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse 100, 66421, Homburg/Saar, Germany. thomas.tschernig@uks.eu.

Funding

Deutsche Forschungsgemeinschaft TRR 152, RTG 2338, KR4338
6 · The paper itself

Abstract

Magnesium is the fourth most abundant cation in the human organism. As a key-player in many enzymatic reactions, magnesium homeostasis disbalance can cause severe disorders. In the early 2000s, the transient receptor potential melastatin channel 6 (TRPM6) was identified as a critical protein in renal Mg

Indexed as

AntibodiesKidneyKidney Tubules, DistalKidney Tubules, ProximalTRPM Cation ChannelsAnimalsImmunohistochemistryMagnesiumMaleMiceMice, Inbred C57BLMice, KnockoutAntibodiesMagnesiumTrpm6 protein, mouseTRPM Cation ChannelsAntibodiesImmunofluorescenceImmunohistochemistryKidneyKnockoutMouseTRPM6

Identifiers

PMID40025338
PMCPMC12350432

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.