Evidence map›Paper›PMID 40025650›Full record

ArticleGut microbes2025

2'-FL and cross-feeding bifidobacteria reshaped the gut microbiota of infants with atopic dermatitis ex vivo and prevented dermatitis in mice post-microbiota transplantation through retinol metabolism activation.

Ce Qi, Zhongxia Li, Huayu Tu, Fang Sun, Wenbo Guo, Can Di, Ruikun He, Xiaolei Ze, Lintao Zhang, Ruijuan Gao and 7 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  4. [Gut microbiota and allergic diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ce QiInstitute of Nutrition and Health, Qingdao University, Qingdao, China.ORCID 0000-0001-8460-6939
Zhongxia LiBYHEALTH Institute of Nutrition & Health, Guangzhou, China.
Huayu TuInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Fang SunPediatrics, Jiaozhou Maternal and Child Health and Family Planning Service Center, Qingdao, China.
Wenbo GuoInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Can DiBYHEALTH Institute of Nutrition & Health, Guangzhou, China.
Ruikun HeBYHEALTH Institute of Nutrition & Health, Guangzhou, China.
Xiaolei ZeBYHEALTH Institute of Nutrition & Health, Guangzhou, China.
Lintao ZhangPediatrics, Jiaozhou Maternal and Child Health and Family Planning Service Center, Qingdao, China.
Ruijuan GaoInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Pengyue HuInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Wenjing YangInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Kexin LiInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Jiayi LiuInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Xiaonan PanInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Zilu JinInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Jin SunInstitute of Nutrition and Health, Qingdao University, Qingdao, China.ORCID 0000-0002-8423-9216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2'-Fucosyllactose (2'-FL), a predominant human milk oligosaccharide, plays a crucial role in the development of the infant gut microbiota and immune system. However, the microbiota of infants with atopic dermatitis (AD) often has difficulty utilizing 2'-FL. Here, we found that strains from human milk,

Indexed as

BifidobacteriumDermatitis, AtopicGastrointestinal MicrobiomeTrisaccharidesVitamin AAnimalsDisease Models, AnimalFatty Acids, VolatileFecal Microbiota TransplantationFemaleHumansInfantMaleMiceMilk, HumanProbiotics2'-fucosyllactoseFatty Acids, VolatileTrisaccharidesVitamin A2’-fucosyllactoseatopic dermatitisbifidobacteriacross-feedingretinol metabolism

Identifiers

PMID40025650
PMCPMC11881859

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.