Evidence map›Paper›PMID 40026491›Full record

SynthesisReviews in cardiovascular medicine2025

Diagnostic and Prognostic Value of Cardiac Magnetic Resonance for Cardiotoxicity Caused by Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis.

Jialian Li, Yanwei Li, Li Tao, Chuan Zhang, Zhong Zuo

Abstract readSystematic Review
In one paragraph

Synthesis in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jialian LiDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0009-0004-8790-5159
Yanwei LiDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0009-0008-3939-6360
Li TaoDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Chuan ZhangDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0000-0001-8579-728X
Zhong ZuoDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0000-0003-3919-0406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The complex process of cardiac magnetic resonance (CMR) and the uncertainty of each parameter in the diagnosis and prognosis of cardiotoxicity limit its promotion in the cardiac evaluation of patients treated with immune checkpoint inhibitors (ICI). Methods: A comprehensive search was conducted across PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), and Cochrane databases for relevant articles published up until September 28, 2024. Results: After screening, 8 articles were included in this study. The analysis revealed that following ICI treatment, the left ventricular global longitudinal strain (GLS) increased significantly [weighted mean difference (WMD) 2.33; 95% confidence interval (CI) 1.26, 3.41; Conclusions: Our findings demonstrate that T1, T2, and GLS increase, while GRS decreases following ICI administration. By consolidating these critical metrics, we propose a streamlined, abbreviated (non-contrast) CMR protocol that can be completed within 15 minutes, thereby facilitating the integration of CMR in cardio-oncology. The PROSPERO registration: CRD42023437238, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023437238.

Indexed as

cardiac magnetic resonancecardiotoxicityglobal longitudinal strainglobal radial strainimmune checkpoint inhibitorsT1T2

Identifiers

PMID40026491
PMCPMC11868891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.