ArticleInternational journal of medical sciences2025
The association between aortic stenosis and the risk of consecutive eyelid inflammatory diseases.
Article in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aortic stenosis (AS) is a fatal cardiovascular disease characterized by an inflammatory response. Blepharitis and hordeolum are two eyelid conditions that also involve ocular inflammation. The aim of this study is to assess the association between AS and the subsequent development of eyelid inflammatory diseases. This retrospective cohort study included individuals diagnosed with AS, who were matched to a control group of non-AS individuals from the TriNetX database. A total of 431,027 individuals were assigned to both the AS and non-AS groups. The primary outcomes of this study were the incidence rates of eyelid inflammatory diseases, including blepharitis and hordeolum. Cox proportional hazards regression was used for statistical analysis. After the follow-up period, 4,464 cases of blepharitis were recorded in the AS group, compared to 3,139 in the non-AS group. Additionally, there were 2,184 cases of hordeolum in the AS group, compared to 1,724 in the non-AS group. Cox proportional hazards regression analysis revealed that the AS group had a significantly higher risk of developing blepharitis (P < 0.001) and hordeolum (P < 0.001) compared to the non-AS group. The AS group also showed significantly higher cumulative probabilities of both blepharitis and hordeolum than the non-AS group (both P < 0.001). In subgroup analyses, AS patients exhibited a higher risk of developing blepharitis than the non-AS population, except for the Asian population and individuals aged 20-45 years. Similarly, the AS group showed a higher risk of developing hordeolum than the non-AS group, with exceptions in the African and Asian populations and individuals aged 20-45 years. In conclusion, the presence of AS is associated with a higher risk of developing subsequent eyelid inflammatory diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.