ArticleACS omega2025
Encapsulation of Ibuprofen by Pickering-Stabilized Antibubbles.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ibuprofen, one of the most widely used nonsteroidal anti-inflammatory drugs, is a poor-tasting and poorly soluble drug. As an alternative approach to overcome these issues, ibuprofen was encapsulated in Pickering antibubbles using two different oils, cyclomethicone and cyclooctane, as processing aids. The amount of the loaded active agent was determined by thermogravimetry (TG), while the analysis of the evolved gases, performed by online coupling of the heating device to an infrared and a mass spectrometer (EGA-FTIR-MS), allowed for describing the drug decomposition mechanism. Although the dissolution profile and zeta potential values were found to be independent of the preparation method, differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD), and Raman microscopy confirmed the occurrence of a slight amorphization of the drug inside the antibubbles. The reported results suggest that this relatively simple encapsulation technique might be an alternative for ibuprofen taste masking and targeted delivery.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.