Evidence map›Paper›PMID 40029460›Full record

ReviewProbiotics and antimicrobial proteins2026

Gerobiotics: Exploring the Potential and Limitations of Repurposing Probiotics in Addressing Aging Hallmarks and Chronic Diseases.

A G M Sofi Uddin Mahamud, Ishtiak Ahammed Tanvir, Md Ehsanul Kabir, Ismam Samonty, Md Anamul Hasan Chowdhury, Md Ashikur Rahman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A G M Sofi Uddin MahamudDepartment of Microbiology, University of Georgia, Athens, GA, 30602, USA. mahamud.ILS@uga.edu.ORCID http://orcid.org/0000-0002-5779-6359
Ishtiak Ahammed TanvirDepartment of Microbiology, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md Ehsanul KabirSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53715, USA. ekabir@wisc.edu.ORCID http://orcid.org/0000-0001-8369-3997
Ismam SamontyDepartment of Agricultural Chemistry, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.
Md Anamul Hasan ChowdhuryDepartment of Food Safety and Regulatory Science, Chung-Ang University, Anseong-Si, Gyeonggi-Do, 17546, Republic of Korea.
Md Ashikur RahmanDepartment of Food Safety and Regulatory Science, Chung-Ang University, Anseong-Si, Gyeonggi-Do, 17546, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As unhealthy aging continues to rise globally, there is a pressing need for effective strategies to promote healthy aging, extend health span, and address aging-related complications. Gerobiotics, an emerging concept in geroscience, offers a novel approach to repurposing selective probiotics, postbiotics, and parabiotics to modulate key aging processes and enhance systemic health. This review explores recent advancements in gerobiotics research, focusing on their role in targeting aging hallmarks, regulating longevity-associated pathways, and reducing risks of multiple age-related chronic conditions. Despite their promise, significant challenges remain, including optimizing formulations, ensuring safety and efficacy across diverse populations, and achieving successful clinical translation. Addressing these gaps through rigorous research, well-designed clinical trials, and advanced biotechnologies can establish gerobiotics as a transformative intervention for healthy aging and chronic disease prevention.

Indexed as

AgingDrug RepositioningProbioticsAnimalsChronic DiseaseHumansLongevityAging hallmarksChronic disease preventionGerobioticsGut microbiota modulationHealth span extensionLongevity pathways

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.