ArticleMethods in molecular biology (Clifton, N.J.)2025
Multifunctional Biocompatible Hyperbranched Polymers as Molecular Imaging Agents and Theranostics.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics.Advanced healthcare materials · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theranostics aims to create a single entity that can detect and treat disease, as well as measure disease and therapeutic progression. This is commonly achieved by the incorporation of molecular imaging reporters, therapeutic agents, and targeting moieties into a single nanomaterial. Hyperbranched polymers have been successfully developed into theranostics owing to the high diversity of functionality that can be introduced through the distinct chemistries of their chain ends, branch points, and sidechains. In this protocol, we introduce the straightforward synthesis and characterization of biocompatible hyperbranched polymers for use as molecular imaging agents and theranostics. We detail a broad range of orthogonal chemistries that have been proven for introducing fluorophores, positron emission tomography (PET) radioisotope chelators, targeting agents, and therapeutics, at precise locations within the polymer structure. We also outline methods for using fluorescence and PET imaging for the preclinical evaluation of new hyperbranched polymer theranostics. These protocols will enable the application of these well-understood polymer materials in new disease applications and models.
Indexed as
Identifiers
40029597What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.