Evidence map›Paper›PMID 40032797›Full record

ArticleDrug safety2025

Opinion Mining of Erowid's Experience Reports on LSD and Psilocybin-Containing Mushrooms.

Ahmed Al-Imam, Riccardo Lora, Marek A Motyka, Erica Marletta, Michele Vezzaro, Jerzy Moczko, Manal Younus, Michal Michalak

Abstract read
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Article in Drug safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmed Al-ImamDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, 61-806, Poznan, Poland. ahmed.al.imam@student.ump.edu.pl.ORCID http://orcid.org/0000-0003-1846-9424
Riccardo LoraSection of Pharmacology, Department of Diagnostics and Public Health, University of Verona, 37134, Verona, Italy.ORCID http://orcid.org/0000-0001-7046-5397
Marek A MotykaInstitute of Sociological Sciences, University of Rzeszow, 35-959, Rzeszów, Poland.ORCID http://orcid.org/0000-0001-6967-0035
Erica Marletta *Section of Pharmacology, Department of Diagnostics and Public Health, University of Verona, 37134, Verona, Italy.ORCID http://orcid.org/0009-0001-1617-7930
Michele Vezzaro *Section of Pharmacology, Department of Diagnostics and Public Health, University of Verona, 37134, Verona, Italy.ORCID http://orcid.org/0009-0009-0702-5247
Jerzy MoczkoDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, 61-806, Poznan, Poland.ORCID http://orcid.org/0000-0002-4164-6196
Manal Younus *Iraqi Pharmacovigilance Centre, Ministry of Health, Baghdad, 10001, Iraq.ORCID http://orcid.org/0000-0001-9475-5700
Michal Michalak *Department of Computer Science and Statistics, Poznan University of Medical Sciences, 61-806, Poznan, Poland.ORCID http://orcid.org/0000-0002-2852-3984

Funding

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu SDUM-DGB 14/05/22 on 5 May 2022
6 · The paper itself

Abstract

backgroundPsychedelics are gaining attention for their therapeutic potential in modern and personalized medicine. Online forums such as Erowid provide valuable user insights, but analyses of these experiences using natural language processing (NLP) remain scarce.

objectiveThis study aims to utilize NLP, including sentiment and lexicon analysis, to examine user-generated experience reports on psilocybin-containing mushrooms and LSD from the Erowid forum.

methodsData from 2188 Erowid users (1161 psilocybin mushrooms and 1027 LSD) was collected via automated web scraping with XPath, CSS selectors, and Selenium WebDriver. The dataset included report titles, substances, and demographics. Sentiment analysis utilized BERT, RoBERTa, and VADER models. Preprocessing involved tokenization, lemmatization, part-of-speech tagging, and stop-word filtering. Lexicon analysis identified themes through recurring n-grams, visualized using Python.

resultsUser demographics revealed comparable ages for psilocybin mushrooms (23.8 ± 0.9 years) and LSD users (20.0 ± 0.6 years), with a predominance of male users. The BERT model predominantly labeled experiences as negative (unfavorable), particularly for mushroom users (p = 0.001). VADER indicated more positive experiences for mushroom users (p < 0.001), while RoBERTa mainly classified experiences as negative or neutral. Significant gender differences were found only with VADER, where more male users expressed positive opinions about psilocybin mushrooms (74.09% versus 65.52%, p < 0.021). The VADER model yielded more polarized results, whereas RoBERTa's cautious classifications indicate its suitability for analyzing lengthy and complex psychedelic reports. Further, RoBERTa outperformed other transformer-based models, achieving the highest accuracy. Lexicon analysis revealed emotional, sensory, and temporal themes, with psilocybin reports emphasizing introspection and time dilation phenomenon, while LSD reports highlighted memory issues and cognitive disorientation.

conclusionsSentiment analysis showed that VADER produced more polarized results, while RoBERTa offered cautious classifications with the highest accuracy. Lexicon analysis revealed shared themes, with mushroom reports focusing on introspection and time dilation perception, while those of LSD emphasized cognitive disturbances. This study highlights the value of these analyses in understanding psychedelic experiences, informing harm reduction, and guiding policy-making.

Indexed as

AgaricalesData MiningHallucinogensLysergic Acid DiethylamidePsilocybinAdultFemaleHumansMaleNatural Language ProcessingYoung AdultHallucinogensLysergic Acid DiethylamidePsilocybin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.