ArticleBMC pregnancy and childbirth2025
The relationship between maternal oral health parameters, inflammatory blood markers, and the evaluation of their effects on preterm low birth weight.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The intelligent neonatal healthcare: a systematic review of machine learning architectures integrating the internet of medical things and blockchain.Frontiers in artificial intelligence · 2026Pooled it
- The effect of web-based educational intervention on caries-preventive oral health behaviors in pregnant women: an application of the health belief model.BMC public health · 2026Trial
- Foetal Development and Placental Health in Response to Apical Periodontitis Induced in Pregnant Wistar Rats.International endodontic journal · 2026Article
- Predicting Miscarriage Risk Based on Periodontal and Hematological Parameters Using Artificial Neural Network and XGBoost Models.Diagnostics (Basel, Switzerland) · 2026Article
- Prediction of preterm and low birth weight risk using a physiology based artificial neural network integrating hematological, dental, and periodontal index markers: a cross sectional study based on machine learning.BMC pregnancy and childbirth · 2026Article
- Association Between Maternal Periodontitis and Preterm Low Birth Weight in Indian Populations: A Literature Review.International journal of MCH and AIDS · 2026Review
- Association of periodontal diseases with inflammatory markers and gestational diabetes: a case-control study.BMC oral health · 2025Article
- Review of the Safety and Clinical Considerations of Vasoconstrictor Agents in Dental Anesthesia During Pregnancy.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm birth significantly elevates neonatal mortality and morbidity, often resulting in developmental challenges and severe health consequences. Risk factor identification is essential for preventative measures. This research aimed to assess maternal oral health's effects on inflammatory blood markers and determine a possible relationship with preterm low birth weight (PLBW).
methodsThis study employed a cross-sectional and case-control design. A randomized cohort of fifty women who delivered low-birth-weight infants was compared to a matched control group of fifty women who delivered full-term infants. Oral health was evaluated using the DMFT (Decayed, Missing, and Filled Teeth), DMFS (Decayed, Missing, and Filled Surfaces), Plaque Index (PI), Gingival Index (GI), Pocket Depth (PD), and Clinical Attachment Level (CAL). Patient history and relevant hematological data were retrieved from medical records. Logistic regression modeling was conducted on variables exhibiting statistical significance (p < 0.05) following group comparisons.
resultsThe case group showed significantly higher oral health indices than the control group, with median DMFT scores of 7.14 vs. 4.74 (p = 0.013), DMFS scores of 20.58 vs. 12.08 (p = 0.026), PI values of 1.96 vs. 1.18, GI values of 2.03 vs. 1.20, and PD values of 2.61 mm vs. 2.00 mm (all p < 0.001). However, none of these parameters (DMFT, DMFS, PI, GI, or PD) were significant predictors of PLBW (p > 0.05). Weak positive correlations were observed between PI, GI, PD, and leukocyte counts (r = 0.240, p = 0.016; r = 0.248, p = 0.013; and r = 0.220, p = 0.028, respectively).
conclusionsConsidering the study's limitations, the principal results suggest a statistically significant difference in oral health, with women delivering low birth weight infants exhibiting poorer outcomes than control groups. Analysis of secondary outcomes indicates that oral health is not an independent predictor of preterm birth; instead, its contribution may be indirect and through systemic inflammation. Effective collaboration between obstetricians and dentists is crucial for the early detection and management of oral health issues in pregnant patients. Prioritizing the creation of public health policies designed to reduce the incidence of preterm births and strengthen maternal-fetal well-being is essential. CLINICAL TRIAL NUMBER: Not applicable.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.