Evidence map›Paper›PMID 40033890›Full record

ArticleMagnetic resonance in medicine2025

Free-breathing hepatic 2D magnetic resonance elastography.

Jiahui Li, Marzanna Obrzut, Jie Chen, Bogdan Dzyubak, Kevin J Glaser, Ziying Yin, Jun Chen, Yuan Le, Alina M Allen, Sudhakar K Venkatesh and 4 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Imaging Evaluation for Steatotic Liver Disease.Korean journal of radiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiahui LiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-4889-0714
Marzanna ObrzutDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Jie ChenDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Bogdan DzyubakDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Kevin J GlaserDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Ziying YinDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-3235-966X
Jun ChenDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Yuan LeDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-1444-8792
Alina M AllenDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Sudhakar K VenkateshDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Armando ManducaDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-9411-5671
Vijay H ShahDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Richard L EhmanDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0001-7041-5074
Meng YinDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

Funding

Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)R01EB017197 · NIBIB · MAYO CLINIC ROCHESTER · PI YIN, MENG · 2014 to 2025
$4.3M
Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
Quantitative characterization of the liver-pancreas axis in diabetes via multiparametric magnetic resonance elastographyR01DK136731 · NIDDK · MAYO CLINIC ROCHESTER · PI Meng Yin · 2023 to 2026
$1.6M
Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastographyR01DK132718 · NIDDK · MAYO CLINIC ROCHESTER · PI Meng Yin · 2023 to 2026
$1.3M
Assessment of Alcoholic Hepatitis with Multiparametric Magnetic Resonance ElastographyUH3AA026887 · NIAAA · MAYO CLINIC ROCHESTER · PI SHAH, VIJAY H., YIN, MENG · 2020 to 2022
$1.1M
Noninvasive detection of NASH by magnetic resonance elastography (MRE)K23DK115594 · NIDDK · MAYO CLINIC ROCHESTER · PI ALLEN, ALINA M · 2018 to 2022
$846k
NIAAA NIH HHS UH3 AA026887NIBIB NIH HHS R01 EB017197NIBIB NIH HHS R37 EB001981NIDDK NIH HHS K23 DK115594NIDDK NIH HHS R01 DK132718NIDDK NIH HHS R01 DK136731NIH HHS K23DK115594NIH HHS R01DK132718NIH HHS R01DK136731NIH HHS R01EB017197NIH HHS R37EB001981NIH HHS UH3AA026887U.S. Department of Defense W81XWH-19-1-0583-01
6 · The paper itself

Abstract

purposeTo evaluate the test-retest repeatability of a rapid, free-breathing two-dimensional (2D) MR elastography (MRE) technique and to assess the reliability of the liver-stiffness measurements compared with conventional breath-hold MREs.

methodsFifteen and 115 participants were enrolled in the technical repeatability and measurement equivalence assessment cohorts, respectively. All participants underwent rapid free-breathing and conventional breath-hold 2D MRE (twice in repeatability cohort) on 1.5T scanners. Both methods have four phase offsets over one harmonic motion cycle at 60 Hz; one and 10 cycles were collected and processed in breath-hold and free-breathing MREs, respectively. The liver stiffness measurements of free-breathing (LS

resultsThe repeatability coefficient of free-breathing 2D MRE is comparable to breath-hold MRE (LS

conclusionsThe nongated, free-breathing, multislice 2D MRE technique can provide reliable liver stiffness measurements compared with conventional breath-hold 2D MRE. It could provide a comfortable alternative method with reliable liver stiffness measurements for patients who have difficulty in suspending respiration.

Indexed as

Elasticity Imaging TechniquesLiverMagnetic Resonance ImagingAdultAgedBreath HoldingFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedReproducibility of ResultsRespirationYoung Adultchronic liver diseasefree breathingliver stiffnessMR elastographyrepeatability

Identifiers

PMID40033890
PMCPMC11972146

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.