ReviewFrontiers in endocrinology2025
Glucose metabolism and endometrium decidualization.
Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Review
- Metabolic Reprogramming at the Maternal-Fetal Interface: Insights from Decidual Stromal Cells and Trophoblasts in Healthy Pregnancy Versus Recurrent Pregnancy Loss.International journal of molecular sciences · 2026Review
- HIF-1α Signaling in Uterine Fibroids: A Central Integrator of Hypoxic, Hormonal, and Fibrotic Pathways.Oxygen (Basel, Switzerland) · 2026Article
- Redefining Endometrial Decidualization: The Central Role of the ER Stress-Immune-Metabolic Axis.International journal of molecular sciences · 2026Review
- Differential Expression and Function of Arginase in Mouse Uterus During Early Pregnancy.International journal of molecular sciences · 2026Article
- Targeting steroid receptor coactivators for the treatment of benign female reproductive disorders.Endocrine connections · 2025Review
- Regulatory Interplay of p53, AMPK, and mTOR in Decidualization: Implications for Reproductive Competence and Cancer Biology.Reproductive sciences (Thousand Oaks, Calif.) · 2025Review
- Review
- Linking the Warburg effect to endometrial receptivity: metabolic parallels in embryo implantation.Frontiers in cell and developmental biology · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prior to embryo implantation, the endometrial stromal cells (ESCs) during the menstrual cycle undergo a significant structural and functional transformation known as decidualization to support conception. During this process, glucose consumption and utilization by endometrial cells increase to meet energy demands. Abnormal glucose metabolism in the endometrium impairs decidualization, leading to pregnancy complications, including implantation failure and pregnancy loss. However, the mechanisms modulating glucose metabolism in endometrial stromal cells during decidualization are still unclear. In this review, we describe the functions and regulation of glucose transporters (GLUTs) involved in glucose uptake, as well as the modulation of key enzymes catalyzing glucose utilization. Moreover, we present recent findings on the role of glucose related metabolites in the decidualization of ESCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.