ReviewHeliyon2025
The effects of sex hormones on BDNF secretion in airway smooth muscle of patients with obstructive pulmonary disease.
Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Relationship Between Contraceptive Use and Respiratory Function in Women: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive pulmonary diseases, including asthma and chronic obstructive pulmonary disease, present significant global public health challenges and substantially impair patients' quality of life. Research indicates that sex hormones and brain-derived neurotrophic factor (BDNF) are pivotal in regulating airway function and inflammatory responses. Specifically, sex hormones modulate the expression and function of BDNF through their receptors, namely estrogen receptors and androgen receptors. Conversely, BDNF enhances cell survival and exerts anti-inflammatory and antioxidant effects, influencing the functionality of sex hormone receptors. This review elucidates the interactions between sex hormones and BDNF in obstructive pulmonary disease, emphasizing their synergistic roles in managing airway inflammation, facilitating tissue repair, and mitigating oxidative stress. Through a thorough examination of these mechanisms, this review aims to foster a more profound comprehension of the potential therapeutic implications for the management of these diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.