Evidence map›Paper›PMID 40034870›Full record

ReviewCurrent developments in nutrition2025

The Effects of Pomegranate Supplementation on Markers of Exercise-Induced Muscle Damage: A Systematic Review and Meta-Analysis.

Saba Belyani, Fatemeh Kazeminasab, Mahnaz Niazi, Reza Bagheri, Mahsa Mahabadi Hesari, Sara K Rosenkranz, Donny M Camera, Fred Dutheil

Abstract readReview
In one paragraph

Review in Current developments in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saba BelyaniDepartment of Human Sciences, Human Nutrition Program, The Ohio State University, Columbus, OH, United States.
Fatemeh KazeminasabDepartment of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.
Mahnaz NiaziDepartment of Nutrition, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Reza BagheriDepartment of Exercise Physiology, University of Isfahan, Isfahan, Iran.
Mahsa Mahabadi HesariDepartment of Exercise Physiology, Faculty of Sport Science, Alzahra University, Tehran, Iran.
Sara K RosenkranzDepartment of Kinesiology and Nutrition Sciences, University of Nevada Las Vegas, Las Vegas, NV, United States.
Donny M CameraDepartment of Health and Biostatistics, Swinburne University, Melbourne, Australia.
Fred DutheilUniversité Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pomegranate supplementation has been shown to reduce oxidative stress and inflammation, with some evidence suggesting it may accelerate recovery from exercise-induced muscle damage (EIMD), including metabolic, mechanical, and neuromuscular recovery. Objectives: This systematic review and meta-analysis aimed to investigate the effects of pomegranate supplementation on markers of EIMD. Methods: A systematic search of Scopus, PubMed, and Web of Science up to January 2024 identified studies evaluating pomegranate supplementation and exercise recovery. Studies involving athletes and nonathletes aged 18-55 were included. Weighted mean differences (WMDs) were calculated for EIMD markers. Study quality was assessed using a modified physiotherapy evidence database scale. This review was registered with the International Prospective Register of Systematic Reviews (ID: CRD42024536905). Results: Ten studies were included in the meta-analysis. Pomegranate supplementation did not significantly affect markers of metabolic recovery, including myoglobin (WMD: -1.344 ng/mL; 95% confidence interval (CI): -4.11, 1.42 ng/mL, Conclusions: Pomegranate supplementation does not appear to enhance overall recovery markers for EIMD but may offer short-term benefits for mechanical muscle damage. Standardizing supplementation regimens, dosages, and exercise protocols is crucial to better understand the potential benefits of pomegranate supplementation in EIMD recovery.

Indexed as

exercisefruitnutritionnutritional supplementsrecovery

Identifiers

PMID40034870
PMCPMC11875170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.