Evidence map›Paper›PMID 40038405›Full record

ArticleScientific reports2025

Association between oxidative balance score and all-cause mortality in stroke survivors.

Jinglin Lei, Zhiyi Liao, Wentao Duan, Qiuli Li, Lili Duan, Hailiang Tang, Hanyao Luo, Hao Huang, Haipeng Li

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jinglin LeiDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Zhiyi LiaoDepartment of Burns and Plastic Surgery, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Wentao DuanDepartment of Critical Care Medicine, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Qiuli LiDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Lili DuanTranslational Medicine Institute, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, China.
Hailiang TangDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Hanyao LuoDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Hao HuangDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China.
Haipeng LiDepartment of Neurology, The Chenzhou Affiliated Hospital, Hengyang Medical School, The First People's Hospital of Chenzhou, University of South China, Chenzhou, 423000, Hunan, China. lihpeng123@gmail.com.

Funding

Hunan Provincial Natural Science Foundation Regional Joint Fund 2023JJ50372major Research Project of National Clinical Key Specialties of Hunan Provincial Health Commission Z2023127Research Project of Hunan Provincial Health Commission D202303077684Xiangnan University College-level Research Project 2022JX109
6 · The paper itself

Abstract

Stroke is the second leading cause of death globally. Oxidative stress plays a critical role in the development of stroke. The Oxidative Balance Score (OBS) is a tool used to assess the combined impact of diet and lifestyle on the body's antioxidant capacity. The study included stroke survivors from the National Health and Nutrition Examination Survey (1999-2018), with a total of 1,781 participants and a median follow-up duration of 6.5 years, during which 786 participants (39.59%) died. The relationship between OBS and all-cause mortality was assessed using the Cox proportional hazards model. The results indicated that individuals in higher OBS quartiles had lower mortality rates. Specifically, patients in the fourth quartile had a 41% reduced risk of all-cause mortality compared to those in the first quartile (HR = 0.59, 95% CI = 0.42-0.84, p = 0.003). Restricted cubic spline analysis revealed a linear inverse relationship between OBS and all-cause mortality. Subgroup analysis further demonstrated that the inverse association persisted across various population subgroups. Overall, our study suggests that higher levels of OBS can reduce the risk of all-cause mortality in stroke survivors and provides new evidence for their diet and lifestyle.

Indexed as

Oxidative StressStrokeSurvivorsAdultAgedAntioxidantsCause of DeathDietFemaleHumansLife StyleMaleMiddle AgedNutrition SurveysProportional Hazards ModelsRisk FactorsAntioxidantsAcute cerebrovascular diseaseAll-cause mortalityAntioxidant capacity

Identifiers

PMID40038405
PMCPMC11880293

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.