Evidence mapPaperPMID 40041784Full record

ReviewHealth science reports2025

Impacts of Curcumin Supplementation on Cardiometabolic Risk Factors in Patients With Polycystic Ovary Syndrome: A Systematic Review and Dose-Response Meta-Analysis.

Shooka Mohammadi, Somayeh Ziaei, Mehrnaz Morvaridi, Motahareh Hasani, Elham Mirtaheri, Farnaz Farsi, Sara Ebrahimi, Elnaz Daneshzad, Javad Heshmati

Abstract readReview
In one paragraph

Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shooka MohammadiNutrition and Metabolic Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID 0000-0001-9157-1922
Somayeh ZiaeiDepartemt of Anesthesia, Imam Reza Hospital Kermanshah University of Medical Sciences Kermanshah Iran.
Mehrnaz MorvaridiSchool of Public Health Iran University of Medical Sciences Tehran Iran.
Motahareh HasaniDepartment of Nutritional Sciences School of Health, Golestan University of Medical Sciences Gorgan Iran.
Elham MirtaheriDepartment of Human Sciences Human Nutrition Program, The Ohio State University Columbus Ohio USA.
Farnaz FarsiMinimally Invasive Surgery Research Center Iran University of Medical Sciences Tehran Iran.
Sara EbrahimiInstitute for Physical Activity and Nutrition School of Exercise and Nutrition Sciences, Deakin University Geelong VIC Australia.
Elnaz DaneshzadNon-Communicable Diseases Research Center Alborz University of Medical Sciences Karaj Iran.
Javad HeshmatiUniversity of Ottawa Heart Institute Ottawa Canada.ORCID 0000-0002-2676-0185

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Patients with polycystic ovary syndrome (PCOS) commonly have cardiometabolic risk factors. Oxidative stress (OS) significantly contributes to the development of cardiometabolic diseases. Curcumin (CUR) exhibits antioxidant properties that aid in OS regulation. This systematic review and dose-response meta-analysis of randomized clinical trials (RCTs) evaluated the effects of CUR supplementation on cardiometabolic risk factors in women with PCOS. Methods: A systematic search across various databases was implemented to identify eligible RCTs published until January 2024. A meta-analysis was conducted employing a random-effects model. Results: Eight RCTs were included in the meta-analysis. It was indicated that CUR supplementation substantially reduced fasting blood sugar (FBS) (standardized mean difference [SMD]: -0.40 mg/dL, 95% confidence interval [CI]: -0.59, -0.21; Conclusion: This study revealed that CUR may have the potential to enhance cardiometabolic health by reducing hyperglycemia, insulin resistance, and serum TC levels in women with PCOS.

Indexed as

cardiometaboliccardiovascularcurcuminpolycystic ovary syndrome

Identifiers

PMID40041784
PMCPMC11872691

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.