Evidence map›Paper›PMID 40041866›Full record

ArticleFrontiers in microbiology2025

Dietary

Airong Dong, Xuemei Ding, Jianping Wang, Qiufeng Zeng, Shiping Bai, Yan Liu, Yue Xuan, Shanshan Li, Yadong Mu, Huanwei Peng and 1 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Frontiers in microbiology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Airong DongKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Xuemei DingKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Jianping WangKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Qiufeng ZengKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Shiping BaiKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Yan LiuKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Yue XuanKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Shanshan LiKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Yadong MuKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Huanwei PengKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Keying ZhangKey Laboratory of Animal Disease-Resistance Nutrition, Key Laboratory of Sichuan Province, Ministry of Agriculture and Rural Affairs, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: A total of 180 Lohmann pink laying hens, aged 80 weeks, were randomly assigned to five groups and fed either a basal diet (PA0) or basal diets supplemented with PA at concentrations of 50, 100, 150, and 200 mg/kg (PA50, PA100, PA150, and PA200). Results: Compared to the PA0 group, PA did not have a significant effect on the production performance of laying hens ( Discussion: Additionally, cecal metabolomic analysis indicated that following the addition of PA, the pathways enriched with differential metabolites were primarily related to arginine and proline metabolism. Therefore, PA has the potential to improve intestinal morphology and flora, mitigate intestinal inflammatory factors, and strengthen intestinal barrier function. These benefits are attributed to the modulation of arginine and proline metabolic pathways, with optimal effects observed at an addition of 50 mg/kg.

Indexed as

aged laying hensegg productiongut microbiotametabolomePediococcus acidilactici

Identifiers

PMID40041866
PMCPMC11877211

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.