Evidence map›Paper›PMID 40041885›Full record

ArticleActa pharmaceutica Sinica. B2025

Cerebral endothelial 3-mercaptopyruvate sulfurtransferase improves ischemia-induced cognitive impairment

Li Zhu, Yi Huang, Jing Jin, Rongjun Zou, Rui Zuo, Yong Luo, Ziqing Song, Linfeng Dai, Minyi Zhang, Qiuhe Chen and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. CIITA/PRMT5 promote CD4BMC medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li ZhuSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Yi HuangDepartment of Stomatology, the First Affiliated Hospital, the School of Dental Medicine, Jinan University, Guangzhou 510632, China.
Jing JinInstitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100700, China.
Rongjun ZouThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Rui ZuoSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Yong LuoSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Ziqing SongSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Linfeng DaiSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Minyi ZhangSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Qiuhe ChenSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Yunting WangDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204-5037, USA.
Wei WangSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.
Rongrong HeGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.
Yang ChenSchool of Pharmaceutics, Guangzhou University of Chinese Medicine, Guangzhou Higher Education Mega Center, Guangzhou 510000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The catalytic activity of 3-mercaptopyruvate (3MP) sulfurtransferase (MPST) converts 3MP to hydrogen sulfide (H

Indexed as

3-Mercaptopyruvate sulfurtransferaseCalpain2Cerebral endotheliumCognitionHydrogen sulfideNeuronProtein phosphatase 2A

Identifiers

PMID40041885
PMCPMC11873647

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.