Evidence map›Paper›PMID 40043899›Full record

ReviewAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2025

Diagnosis and Management of Dementia for the Nephrology Clinician: A Review.

Christine K Liu, Katharine L Cheung, Manjula Kurella Tamura

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christine K LiuSection of Geriatric Medicine, Division of Primary Care and Population Health, School of Medicine, Stanford University, Stanford, California; Geriatric Research and Education Clinical Center, Veteran Affairs Palo Alto Health Care System, Palo Alto, California. Electronic address: chliu1@stanford.edu.
Katharine L CheungDivision of Nephrology, Larner College of Medicine, University of Vermont, Burlington, Vermont; Center on Aging, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Manjula Kurella TamuraDivision of Nephrology, School of Medicine, Stanford University, Stanford, California; Geriatric Research and Education Clinical Center, Veteran Affairs Palo Alto Health Care System, Palo Alto, California.

Funding

A Research Mentoring Program in Geriatric Rehabilitative CareK24AG069176 · NIA · HARVARD MEDICAL SCHOOL · PI BEAN, JONATHAN F · 2020 to 2024
$661k
A Mentoring Program in Kidney Care for Older AdultsK24AG073615 · NIA · STANFORD UNIVERSITY · PI MANJULA KURELLA TAMURA · 2022 to 2026
$651k
NIA NIH HHS K24 AG069176NIA NIH HHS K24 AG073615
6 · The paper itself

Abstract

Dementia describes when a person has cognitive limitations that impede function. Persons with kidney disease are unduly impacted by dementia: up to 87% of the dialysis population has cognitive impairment. In this review, we discuss the diagnosis and management of dementia, including the role of cerebrovascular disease and other risk factors. We review the available screening tools for the diagnosis of dementia. We discuss how the diagnosis of dementia differs from the diagnosis of mild cognitive impairment and also detail how delirium and depression can mimic dementia. In terms of treatments for dementia, we highlight 4 components. First, we describe pharmacologic treatments for the management of dementia, including the cholinesterase inhibitors N-methyl-d-aspartate antagonists as well as the newer antiamyloid antibody drugs for Alzheimer dementia. Second, we discuss the importance of nonpharmacologic interventions for the management of dementia, especially exercise. Third, we review approaches for the behavioral and neuropsychiatric symptoms associated with dementia, including potential medication management. Fourth, we highlight the essential and valuable role of caregivers in both the diagnosis and management of dementia. We conclude with key considerations about the impact of dementia for persons receiving dialysis and the role of dementia in kidney transplant evaluation.

Indexed as

DementiaKidney Failure, ChronicCholinesterase InhibitorsDisease ManagementHumansNephrologyRenal DialysisCholinesterase InhibitorsAlzheimer’s diseaseAlzheimer’s disease and related dementiasanti-amyloidcaregiverscare partnerscholinesterase inhibitorschronic kidney diseasecognitioncognitive impairmentdeliriumdementiadepressiondialysiskidneykidney transplantmild cognitive impairmentmixed dementiaNMDA agonistrenalrenal transplanturemiavascular dementia

Identifiers

PMID40043899
PMCPMC12182998

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.