Evidence map›Paper›PMID 40044110›Full record

ReviewAnnals of coloproctology2025

Diagnostic performance of various radiological modalities in the detection of sarcopenia within Asian populations: a systematic review.

Shi Wei Ang, Jacqueline Liew, Vanessa Malishree Dharmaratnam, Vanessa Yi Jean Yik, Shawn Kok, Syed Aftab, Cherie Tong, Hui Bing Lee, Shimin Mah, Clement Yan and 2 more

Abstract readReview
In one paragraph

Review in Annals of coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shi Wei AngYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jacqueline LiewYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Vanessa Malishree DharmaratnamDepartment of General Surgery, Sengkang General Hospital, Singhealth, Singapore.
Vanessa Yi Jean YikDuke-NUS Medical School, Singapore.
Shawn KokDepartment of Radiology, Sengkang General Hospital, Singhealth, Singapore.
Syed AftabDepartment of Radiology, Sengkang General Hospital, Singhealth, Singapore.
Cherie TongDepartment of Dietetics, Sengkang General Hospital, Singhealth, Singapore.
Hui Bing LeeDepartment of Dietetics, Sengkang General Hospital, Singhealth, Singapore.
Shimin MahDepartment of Physiotherapy, Sengkang General Hospital, Singhealth, Singapore.
Clement YanDepartment of Physiotherapy, Sengkang General Hospital, Singhealth, Singapore.
Bin-Tean TehNational Cancer Centre Singapore, Singhealth, Singapore.
Frederick H KohDepartment of General Surgery, Sengkang General Hospital, Singhealth, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiagnosing sarcopenia necessitates the measurement of skeletal muscle mass. However, guidelines lack a standardized imaging modality with thresholds validated among Asians. This systematic review compared ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and bioelectrical impedance analysis (BIA)/body composition monitoring in the detection of sarcopenia within Asian populations.

methodsPubMed and Embase were systematically searched for studies analyzing ultrasonography, CT, MRI, and BIA in diagnosing sarcopenia among Asians. Study quality was assessed using the Newcastle-Ottawa scale.

resultsPooled findings from 21,598 patients across 25 studies were examined. In receiver operating characteristic analysis, ultrasound displayed a pooled mean area under the curve (AUC) of 0.767 (95% confidence interval [CI], 0.709-0.806), with mean sensitivity of 81.1% (95% CI, 0.744-0.846) and specificity of 73.1% (95% CI, 0.648-0.774), for detecting sarcopenia in Asian populations. CT exhibited an AUC of 0.720 (sensitivity, 54.0%; specificity, 92.0%). MRI demonstrated an AUC of 0.839 (sensitivity, 67.0%; specificity, 66.0%). BIA displayed an AUC of 0.905 (95% CI, 0.842-0.968), 80.7% sensitivity (95% CI, 0.129-0.679), and 82.4% specificity (95% CI, 0.191-0.633).

conclusionsVarious modalities aid in diagnosing sarcopenia, and selection should be individualized. Although only BIA and dual-energy x-ray absorptiometry are recommended by the Asian Working Group for Sarcopenia and the European Working Group on Sarcopenia in Older People, ultrasound imaging may hold diagnostic value for sarcopenia in the Asian population. In certain groups, diagnostic use of CT and MRI is warranted. Future research can standardize and validate modality-specific thresholds and protocols within Asian populations.

Indexed as

AsianDiagnosisRisk assessmentSarcopenia

Identifiers

PMID40044110
PMCPMC11894942

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.