ReviewAJNR. American journal of neuroradiology2025
Clinical Translation of Hyperpolarized
Abstract readReview
In one paragraph
Review in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic Imaging as Future Technology and Innovation in Brain-Tumour Surgery: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Clinical Applications of Hyperpolarized Magnetic Resonance Imaging in Brain Tumors: Current Evidence and Future Opportunities.Cancers · 2026Review
- First worldwide multicenter validation of the POLARIS preclinical polarizer across biological models and imaging paradigms.Research square · 2026Article
- Development and First-in-Human Translation of Hyperpolarized [1-Sensors (Basel, Switzerland) · 2026Article
- Evaluation of treatment response in patients with recurrent grade 4 glioma using hyperpolarized [1-Research square · 2026Article
- Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment.Neuro-oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Adam W AutryFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California adam.autry@ucsf.edu.ORCID https://orcid.org/0000-0002-7062-4965
Yaewon KimFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-1016-1572
Duy DangFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.
Hsin-Yu ChenFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0002-2765-1685
James B SlaterFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.
Robert A BokFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.
Duan XuFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-0550-4235
Janine M LupoFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0002-0051-6387
Jeremy W GordonFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-2760-4886
Peder E Z LarsonFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-4183-3634
Daniel B VigneronFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0001-5795-8699
Yan LiFrom the Department of Radiology and Biomedical Imaging (A.W.A., Y.M., D.D., H.-Y.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-2145-2869
Susan M ChangDepartment of Neurological Surgery (B.B.V., S.M.C.), University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0009-0001-2084-3959
Funding
Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2002 to 2026
$57.4MProject 4: Multi-modality Metabolic Imaging for Monitoring Molecular Sub-types of GliomaP01CA118816 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang, Janine Marie Lupo · 2007 to 2026
$44.7MTR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9MMultimodality Neuroimaging Evaluation of Cognitive Functioning in Lower Grade AstrocytomaR01CA273028 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORDON, JEREMY WILLIAM, LI, YAN · 2022 to 2025
$3.3MQuantitative Steady-State and Dynamic Metabolic MRI for Evaluating Patients with GliomaR01CA262630 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang, Albert Chen · 2022 to 2026
$3.3MUpgrade of an Obsolete 3.35T DNP Polarizer to enable new HP C-13 Technology DevelopmentS10OD025077 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VIGNERON, DANIEL B · 2020 to 2020
$1.7MNCI NIH HHS P01 CA118816NCI NIH HHS P50 CA097257NCI NIH HHS R01 CA262630NCI NIH HHS R01 CA273028NIBIB NIH HHS P41 EB013598NIH HHS S10 OD025077
Abstract
Hyperpolarized carbon-13 (HP-
Indexed as
Brain NeoplasmsCarbon IsotopesGliomaMagnetic Resonance ImagingAnimalsHumansTranslational Research, BiomedicalCarbon-13Carbon Isotopes
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.