Evidence map›Paper›PMID 40044640›Full record

SynthesisTranslational psychiatry2025

Interventions for suicidal and self-injurious related behaviors in adolescents with psychiatric disorders: a systematic review and meta-analysis.

Junjie Lu, Jun Huang, Wanting Gao, Zexin Wang, Nan Yang, Yingbin Luo, Junxin Guo, Weng Ian Phoenix Pang, Grace Ka In Lok, Wenwang Rao

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junjie LuDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China.ORCID http://orcid.org/0000-0002-3241-6698
Jun HuangDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China.ORCID http://orcid.org/0009-0005-9135-9872
Wanting GaoDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China.ORCID http://orcid.org/0009-0000-9487-5120
Zexin WangFaculty of Health Sciences and Sports, Macao Polytechnic University, Macau SAR, China.ORCID http://orcid.org/0009-0009-3426-1579
Nan YangFaculty of Health Sciences and Sports, Macao Polytechnic University, Macau SAR, China.ORCID http://orcid.org/0009-0007-0605-3217
Yingbin LuoDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China.ORCID http://orcid.org/0009-0000-9669-5115
Junxin GuoDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China.ORCID http://orcid.org/0009-0000-1762-5865
Weng Ian Phoenix PangFaculty of Health Sciences and Sports, Macao Polytechnic University, Macau SAR, China.ORCID http://orcid.org/0009-0008-9745-0708
Grace Ka In LokMacao Polytechnic University, Peking University Health Science Center-Macao Polytechnic University Nursing Academy, Macau SAR, China. kilok@mpu.edu.mo.ORCID http://orcid.org/0000-0001-8726-5113
Wenwang RaoDepartment of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong Province, China. raoww@stu.edu.cn.ORCID http://orcid.org/0000-0002-3514-3082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a leading cause of adolescent death, suicidal and self-injurious related behaviors (SSIRBs) is a devastating global health problem, particularly among patients with psychiatric disorders (PDs). Previous studies have shown that multiple interventions can alleviate symptoms and reduce risks. This review aimed to provide a systematic summary of interventions (i.e., medication, physical therapy, psychosocial therapy) for the treatment of SSIRBs among Chinese adolescents with PDs. From inception to September 17, 2023, twelve databases (PubMed, CINAHL, ScienceDirect, PsycINFO, EMBASE, Cochrane Library, Clinical Trial, Web of Science, CEPS, SinoMed, Wanfang and CNKI) were searched. We qualitatively and quantitatively synthesized the included studies. Standardized mean differences (SMDs), risk ratios and their 95% confidence intervals (CIs) used the Der Simonian and Laird random-effects model. Fifty-two studies covering 3709 eligible participants were included. Overall, the commonly used interventions targeting SSIRBs and negative feelings in PDs adolescents with SSIRBs included psychosocial therapy (e.g., cognitive behavioral therapy), medication (e.g., antidepressants), and physiotherapy (e.g., repetitive transcranial magnetic stimulation). Importantly, quetiapine fumarate in combination with sodium valproate (SV) had positive effects on reducing self-injury behaviors score [SMD: -2.466 (95% CI: -3.305, -1.628), I

Indexed as

Mental DisordersSelf-Injurious BehaviorAdolescentCognitive Behavioral TherapyHumans

Identifiers

PMID40044640
PMCPMC11883024

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.