Evidence mapPaperPMID 40045148Full record

ArticleEuropean journal of pediatrics2025

Age differences in prevalence and symptoms of post-COVID-19 condition among children: a prospective cohort study.

Yixin Wu, Xiangrong Sun, Jingyun Yang, Hailin Fan, Ouxuan Jin, Liwei Tang, Meixian Zhang, Lizhen Wang

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Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yixin Wu *Department of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Xiangrong Sun *Department of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Jingyun Yang *Department of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Hailin FanDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Ouxuan JinDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Liwei TangDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China.
Meixian ZhangDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China. meixian0116@163.com.
Lizhen WangDepartment of Pediatrics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000, China. wanglz@enzemed.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some individuals experience unexplained, persistent, or newly developed symptoms after coronavirus disease 2019 (COVID-19), known as post-COVID-19 condition (PCC). We explored the age-related prevalence, symptoms, and associated factors for PCC in children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This prospective cohort study enrolled children with SARS-CoV-2 infection between December 7, 2022, and January 31, 2023. The participants were assessed via telephone 6 months post-SARS-CoV-2 diagnosis. PCC in children was diagnosed according to the World Health Organization definition. In total, 1084 patients were eligible for matching and follow-up. Eventually, 785 patients (follow-up rate, 72.4%) completed the follow-up. The incidence of PCC among pediatric patients with COVID-19 was 8%. The most common symptom reported by children diagnosed with PCC in all age groups was fatigue. For patients aged 0-2 years, the presence of gastrointestinal symptoms (OR,6.323; 95% CI, 1.549-25.818) and neurological symptoms (OR, 3.816; 95% CI, 1.075-13.545) at the onset of COVID-19 were associated factors for PCC. For patients aged 3-6 years, no associated factors associated with PCC were identified. For patients aged 7-12 years, preexisting comorbidities (OR, 6.869; 95% CI, 2.209-21.360) were associated factors for PCC. For patients aged 13-17 years, female sex (OR, 3.635; 95% CI, 1.164-11.355) and preexisting comorbidities (OR, 6.295; 95% CI, 2.052-19.316) were associated factors for PCC.

conclusionThe incidence of PCC among pediatric patients with COVID-19 was 8%, with fatigue being the most commonly reported symptom across all age groups. The associated factors for PCC varied according to age groups. WHAT IS KNOWN: • Post-COVID-19 condition (PCC) can significantly affect the psychological and physiological health of children. •The characteristics of persistent symptoms and the incidence of PCC varied among children of different age groups. WHAT IS NEW: • Fatigue is the most common symptom of PCC in children of all age groups. • The associated factors for PCC varied according to age group.

Indexed as

COVID-19AdolescentAge FactorsChildChild, PreschoolFatigueFemaleHumansIncidenceInfantInfant, NewbornMalePost-Acute COVID-19 SyndromePrevalenceProspective StudiesSARS-CoV-2Associated factorsCOVID-19FatiguePrevalenceSARS-CoV-2World Health Organization

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PMID40045148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.