Evidence map›Paper›PMID 40045217›Full record

ArticleBMC neurology2025

Prevalence and incidence of multiple sclerosis in healthcare district IV of Asturias, Spain.

Pedro Oliva-Nacarino, Marina Simal Antuña, Carmen Santos Varela, Javier Villafani Echazú, Jessica Fernández Domínguez, Raquel García Rodríguez, Agustín Oterino Durán, Patricia Suarez Santos, Miguel Ángel Llaneza González

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Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pedro Oliva-NacarinoServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain. pedro.oliva@sespa.es.
Marina Simal AntuñaServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain.
Carmen Santos VarelaServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain.
Javier Villafani EchazúServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain.
Jessica Fernández DomínguezServicio de Neurología, Centro Médico de Asturias, Oviedo, Spain.
Raquel García RodríguezServicio de Neurología, Centro Médico de Asturias, Oviedo, Spain.
Agustín Oterino DuránServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain.
Patricia Suarez SantosServicio de Neurología, Hospital San Agustín, Avilés, Spain.
Miguel Ángel Llaneza GonzálezServicio de Neurología, Hospital Universitario Central de Asturias, Oviedo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple sclerosis is an inflammatory demyelinating autoimmune disease of the central nervous system. Studies conducted in recent years point to an increase in its prevalence and a change in the age profile of patients. This study aims to analyse the prevalence and incidence of multiple sclerosis in healthcare district IV of the region of Asturias, in north-western Spain.

methodsWe conducted a retrospective epidemiological study of the population of said healthcare district with a diagnosis of multiple sclerosis according to the 2017 McDonald criteria. The prevalence of the disease was calculated cross-sectionally (prevalence date: December 31, 2022), while the incidence was determined retrospectively over a six-year period, from 2017 to 2022. We gathered data from the registries and databases of the tertiary hospital in healthcare district IV, and from one private hospital. Relevant demographic and clinical data were gathered from electronic records.

resultsThe prevalence of multiple sclerosis in the population studied was 198 cases per 100 000 population. The incidence of multiple sclerosis during the study period (2017-2022) was 6.6 cases per 100 000 person-years. On the prevalence date, 66.5% of patients were women and 82.4% presented relapsing-remitting multiple sclerosis. Mean age was 33.98 years at symptom onset and 50.84 years on the prevalence date.

conclusionsAsturias currently presents the highest multiple sclerosis prevalence rate in Spain; the estimated rate represents an increase with respect to those reported in studies conducted in the same region in the 1990s.

Indexed as

Multiple SclerosisAdolescentAdultAgedCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedPrevalenceRetrospective StudiesSpainYoung AdultAsturiasEpidemiologyIncidenceMultiple sclerosisPrevalenceSpain

Identifiers

PMID40045217
PMCPMC11881357

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.