ArticleSe pu = Chinese journal of chromatography2025
[Determination of glucose in exhaled breath and saliva by ion chromatography].
Article in Se pu = Chinese journal of chromatography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- [Rapid screening and quantitative analysis of 26 soluble sugars in tobacco by ultra performance liquid chromatography-quadrupole-time of flight mass spectrometry].Se pu = Chinese journal of chromatography · 2026Article
- Dynamic Changes in Exhaled Breath Glucose by Condensate Collection During Oral Glucose Tolerance Testing in Healthy Adults.Medical devices (Auckland, N.Z.) · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel noninasive method was developed for determining glucose levels in human exhaled breath and saliva using ion chromatography. This innovative approach involves collecting exhaled breath and saliva samples using a self-designed condensation device and non-stimulative method to ensure minimal participant discomfort. The glucose contents in both exhaled breath condensate (EBC) and saliva were analyzed using ion chromatography, which is highly sensitive and specific. The experimental conditions were optimized, including a condensation temperature of -14 ℃ and an expiratory flow of 15 L/min. A Dionex CarboPac MA1 ion chromatography column (250 mm×4 mm) was used to separate glucose, with the column temperature maintained at 30 ℃. Sodium hydroxide solution (0.8 mol/L) with a pump flow rate of 0.4 mL/min was used as the mobile phase for ion chromatography. Under these conditions, glucose exhibited a good linear relationship in the range of 0.01-20 mg/L, with a correlation coefficient of 0.9999, along with limits of detection (LOD) and quantification (LOQ) of 2.1 and 7.0 μg/L, respectively. The intra- and inter-day precisions of glucose content in exhaled breath and saliva samples of ≤7.5% (
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