Evidence map›Paper›PMID 40045862›Full record

ReviewCurrent medicinal chemistry2025

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.

Geir Bjørklund, Mariia Shanaida, Tetiana Gontova, Emma Gheorghe, Laura Kassym, Assiya Kussainova, Volodymyr Voloshyn, Yuliya Semenova, Roman Lysiuk, Olena Voloshyn and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Geir BjørklundCouncil for Nutritional and Environmental Medicine (CONEM), Mo i Rana, Norway.
Mariia ShanaidaI. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Tetiana GontovaNational University of Pharmacy, Kharkiv, Ukraine.
Emma GheorgheFaculty of Medicine, Ovidius University of Constanta, Constanta, Romania.
Laura KassymDepartment of General Medical Practice with a Course of Evidence-Based Medicine, NJSC "Astana Medical University", Astana, Kazakhstan.
Assiya KussainovaSchool of Medicine, Nazarbayev University, Astana, Kazakhstan.
Volodymyr VoloshynI. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Yuliya SemenovaSchool of Medicine, Nazarbayev University, Astana, Kazakhstan.
Roman LysiukDepartment of Pharmacognosy and Botany, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Olena VoloshynDepartment of Pharmacognosy and Botany, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Volodymyr ShanaidaCONEM Ukraine Natural Drugs Research Group, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Tony HanganFaculty of Medicine, Ovidius University of Constanta, Constanta, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin is the human body's largest organ, protecting it from various environmental threats. At the same time, it is the most accessible organ of the body, which ensures the reception of stimuli and contact with the environment. Such common signs of skin aging, such as wrinkles, fine lines, and discoloration, result from both extrinsic and intrinsic factors that act for a long time. If the skin does not look well enough, it is worth investigating whether minerals or trace elements are deficient. The positive role of some minerals (calcium, potassium, sodium, sulfur, and magnesium) and trace elements (iron, zinc, selenium, copper, manganese, and silicon) was found in maintaining skin health. There are also a variety of skin conditions, such as inflammatory disorders (eczema, psoriasis), acne, lichen planus, vitiligo, alopecia areata, or even skin cancer, which require specific approaches for their prevention and treatment considering the saturation of the body and the skin with mineral elements. They could be supplied internally (through adequate nutrition or food additives) or externally (by application of cosmetics). Some aspects of the danger of the toxic trace elements used in cosmetics are also described in this review.

Indexed as

MineralsSkinSkin DiseasesTrace ElementsHumansMineralsTrace Elementsantioxidantsdermatologylichen planusnutritional deficiencies.Skin healthtrace elements

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.