Evidence mapPaperPMID 40046609Full record

ArticleGlobal & regional health technology assessment

D.I.Ri.M.O. project: deprescription, inappropriateness evaluation and therapeutic reconciliation in hospital medicine.

Maria Giulia Pollice, Luca Degli Esposti, Cataldo Procacci, Salvatore Lenti, Domenica Ancona, Carmela Nappi, Biagio Lacolare, Anna Maria Tesse, Domenico Leuci, Mara Masullo and 1 more

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Article in Global & regional health technology assessment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Maria Giulia PolliceDepartment of Pharmacy, Pharmaceutical Sciences, University Aldo Moro, Bari - Italy.ORCID https://orcid.org/0009-0005-1284-0343
Luca Degli EspostiCliCon S.r.l. Società Benefit Health, Economics and Outcomes Research, Bologna - Italy.ORCID https://orcid.org/0000-0002-7020-6659
Cataldo ProcacciPharmaceutical Department of the Barletta-Andria-Trani Local Health Authority, Trani - Italy.ORCID https://orcid.org/0000-0001-9505-4340
Salvatore LentiInternal Medicine Unit Andria Hospital, Barletta-Andria-Trani Local Health Authority, Andria - Italy.
Domenica AnconaPharmaceutical Department of the Barletta-Andria-Trani Local Health Authority, Trani - Italy.
Carmela NappiCliCon S.r.l. Società Benefit Health, Economics and Outcomes Research, Bologna - Italy.ORCID https://orcid.org/0009-0003-9670-3308
Biagio LacolareCliCon S.r.l. Società Benefit Health, Economics and Outcomes Research, Bologna - Italy.
Anna Maria TesseInternal Medicine, University of Foggia, Foggia - Italy.
Domenico LeuciInternal Medicine Unit Andria Hospital, Barletta-Andria-Trani Local Health Authority, Andria - Italy.
Mara MasulloClinical Risk Management, Quality and Bed Management, Barletta-Andria-Trani Local Health Authority, Trani - Italy.
Domenico TricaricoDepartment of Pharmacy, Pharmaceutical Sciences, University Aldo Moro, Bari - Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In the Italian healthcare landscape, the management of chronic pathologies is a priority. Often, the elderly patient suffers from several pathologies at once and is commonly on polytherapy: this can easily bring potentially harmful errors in drug therapy. The D.I.Ri.M.O. project took place in an Internal Medicine department and aimed to reduce medication errors and improve the state of health through the Pharmacological Reconciliation procedure. Methods: From June to October 2022, the team archived therapies for 70 hospitalized patients aged over 65 years and suffering from two or more chronic diseases. For each patient enrolled, the team developed a reconciliation board; afterward, the physician and the pharmacist proceeded to remodulate therapies, especially in those patients with serious interactions. Results: The team collected 287 drug interactions and then classified them according to the Intercheck Web software classification: 36 class D (very serious), 49 class C (major), 174 class B (moderate), and 28 class A (minor). The modified therapies at discharge were 77.14%. This restriction brought about the removal of unnecessary drugs. After six months, the team observed an improvement in the health conditions of the patients enrolled. Conclusions: By increasing the patient's awareness and reducing the number of potentially inappropriate prescriptions, it is possible to improve the effectiveness of therapies. It is also possible to look at a saving policy to make the economic resources better allocated.

Indexed as

ComorbidityDeprescriptionElderly patientHospitalizationPharmacological reconciliation­Polytherapy

Identifiers

PMID40046609
PMCPMC11880813

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.